Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

Schizophrenia is an aetiologically complex disorder arising from the interaction of a range of
factors acting at various stages of life. Schizophrenic individuals inherit genes that cause …

The idea that schizophrenia has its origins in early development dates back at least to the
modern classification of the syndrome by Emil Kraepelin and Eugen Bleuler, both of whom …

Schizophrenia is known to be one of the most devastating and chronic mental conditions.
The onset of this syndrome, which includes heterogeneous subsets of disease conditions, is …

▪ Abstract A combination of genetic susceptibility and environmental perturbations appear to
be necessary for the expression of schizophrenia. In addition, the pathogenesis of the …

In recent years, several pathophysiological models of schizophrenia, ie the early and late
brain neurodevelopmental and post-illness onset neurodegenerative models, have been …

It is widely accepted that schizophrenia originates from abnormalities occurring during the
early stages of neural development. Although large studies have revealed behavioral …

The etiology of schizophrenia has been the focus of intensive research for a long time.
Perspectives have changed drastically with the development of new investigative …

For the first time, there is a pathogenic hypothesis of schizophrenia based upon reasonable
empirical data. The hypothesis is that schizophrenia is a disorder arising from aberrant brain …

While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …