[HTML][HTML] Molecular pathways of major depressive disorder converge on the synapse

GR Fries, VA Saldana, J Finnstein, T Rein - Molecular Psychiatry, 2023 - nature.com
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

The cellular and molecular basis of major depressive disorder: towards a unified model for understanding clinical depression

E Pitsillou, SM Bresnehan, EA Kagarakis… - Molecular biology …, 2020 - Springer
Major depressive disorder (MDD) is considered a serious public health issue that adversely
impacts an individual's quality of life and contributes significantly to the global burden of …

Linking molecules to mood: new insight into the biology of depression

V Krishnan, EJ Nestler - American Journal of Psychiatry, 2010 - Am Psychiatric Assoc
Major depressive disorder is a heritable psychiatric syndrome that appears to be associated
with subtle cellular and molecular alterations in a complex neural network. The affected …

Pathogenesis of depression: insights from human and rodent studies

C Ménard, GE Hodes, SJ Russo - Neuroscience, 2016 - Elsevier
Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

[PDF][PDF] Current understanding of the neurobiology of major depressive disorder

AL Chiriţă, V Gheorman, D Bondari, I Rogoveanu - Rom J Morphol Embryol, 2015 - rjme.ro
Depression is highly prevalent worldwide and associated with significant morbidity and
mortality. Approximately 340 million people worldwide suffer from depression at any given …

Neuronal correlates of depression

D Chaudhury, H Liu, MH Han - Cellular and Molecular Life Sciences, 2015 - Springer
Major depressive disorder (MDD) is a common psychiatric disorder effecting approximately
121 million people worldwide and recent reports from the World Health Organization (WHO) …

Dysregulation of brain dopamine systems in major depressive disorder

NC Delva, GD Stanwood - Experimental Biology and …, 2021 - journals.sagepub.com
Major depressive disorder (MDD or depression) is a debilitating neuropsychiatric syndrome
with genetic, epigenetic, and environmental contributions. Depression is one of the largest …

Neurobiological basis of depression: an update

M Kalia - Metabolism, 2005 - Elsevier
The past 5 years have seen unprecedented advances in our knowledge about the
neurobiology of depression. Significant breakthroughs have been made in genomics …

Molecular aspects of depression: a review from neurobiology to treatment

GRV Boas, RB de Lacerda, MM Paes, P Gubert… - European journal of …, 2019 - Elsevier
Major depressive disorder (MDD), also known as unipolar depression, is one of the leading
causes of disability and disease worldwide. The signs and symptoms are low self‑esteem …

The neurobiology of depression: an integrated overview from biological theories to clinical evidence

F Ferrari, RF Villa - Molecular neurobiology, 2017 - Springer
Depressive disorders are heterogeneous diseases, and the complexity of symptoms has led
to the formulation of several aethiopathological hypotheses. This heterogeneity may account …