Knowledge of the fundamental epigenetic mechanisms governing gene expression and
cellular phenotype are sufficiently advanced that novel insights into the epigenetic control of …

Epigenetics is a term that encompasses a variety of regulatory processes that are able to
crosstalk in order to influence gene expression and cell phenotype in response to …

Simple Summary Cellular identity and function depends on the correct and specific
expression of genetic information. Different epigenetic mechanisms including DNA …

Novel insights into the epigenetic control of chronic liver diseases are now emerging.
Recent advances in our understanding of the critical roles of DNA methylation, histone …

Due to the advances made in research based on next generation sequencers, it is now
possible to detect and analyze epigenetic abnormalities associated with cancer. DNA …

Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, being the sixth
most commonly diagnosed cancer and the fourth leading cause of cancer-related death. As …

Epigenetic mechanisms maintain heritable changes in gene expression and chromatin
organization over many cell generations. Importantly, deregulated epigenetic mechanisms …

In recent years, large scale genomics and genome-wide studies using comprehensive
genomic tools have reshaped our understanding of cancer evolution and heterogeneity …

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and
has a high fatality rate. Genetic and epigenetic aberrations are commonly observed in HCC …

Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults.
Chronic infections with hepatitis B (HBV) and C (HCV) viruses and alcohol abuse are the …