Despite much recent progress, prostate cancer continues to represent a major cause of
cancer-related mortality and morbidity in men. Since early studies on the role of the …

Background With continuous progress over the past few decades in understanding
diagnosis, treatment, and genetics, much has been learned about the prostate cancer …

Prostate cancer is a major health problem as it continues to be the most frequently
diagnosed cancer in men in the Western world. While improved early detection significantly …

Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …

Prostate cancer is the sixth most common cancer in the world and the third leading cause of
cancer in men. The increase in the understanding of prostate carcinogenesis over the past …

Prostate cancers are highly prevalent in the developed world, with inheritable risk
contributing appreciably to tumour development. Genomic heterogeneity within individual …

Recent genetics and genomics studies of prostate cancer have helped to clarify the genetic
basis of this common but complex disease. Genome-wide studies have detected numerous …

Over the past several years, analyses of data from high-throughput studies have elucidated
many fundamental insights into prostate cancer biology. These insights include the …

Context Recent studies focused on the molecular characterization of metastatic prostate
cancer have identified genomic subsets and emerging resistance patterns. Detection of …

Simple Summary Prostate cancer affects men of all racial and ethnic groups and leads to
higher rates of mortality in those belonging to a lower socioeconomic status due to late …