BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …

Abstract STUDY QUESTION Are there DNA methylation alterations in sperm that could
explain the reduced biological fertility of male partners from couples with unexplained …

Considering the widespread use of assisted reproductive techniques (ART), DNA
methylation of specific genes involved in spermatogenesis achieves increasingly clinical …

Sperm DNA methylation abnormalities have been detected in oligozoospermic men.
However, the association between sperm DNA methylation defects, sperm parameters and …

Data about the entire sperm DNA methylome are limited to two sperm donors whereas
studies dealing with a greater number of subjects focused only on a few genes or were …

Infertility is a significant problem for human reproduction, with males and females equally
affected. However, the molecular mechanisms underlying male infertility remain unclear …

Objective To evaluate the relationship between epigenetic patterns in sperm and fecundity.
Design Prospective study. Setting Academic andrology and in vitro fertilization laboratory …

Background Several studies have reported an association between male infertility and
aberrant sperm DNA methylation patterns, in particular in imprinted genes. In a recent …

The influence of aberrant sperm DNA methylation on the reproductive capacity of couples
has been postulated as a cause of infertility. This study compared the DNA methylation of …

DNA methylation is an epigenetic modification of the genome. The purpose of this study was
to determine the influence of cigarette‐smoking on sperm DNA methylation from a …