Objectives: The purpose of this study was to investigate the impact of renin-angiotensin
system blockade therapy on outcomes in aortic stenosis (AS). Background: Angiotensin …

Background Experimental studies revealed that renin–angiotensin system (RAS) could play
a crucial role in the pathophysiology of aortic stenosis (AS). The objectives of this study were …

Background Renin–angiotensin system inhibition (RASI) is frequently avoided in aortic
stenosis (AS) patients because of fear of hypotension. We evaluated if RASI with …

Aortic stenosis (AS) is a common valvular heart disease in the aging population that is
characterized by a variable period of asymptomatic phase before development of symptoms …

BACKGROUND: Animal models have demonstrated a benefit of angiotensin-converting
enzyme inhibitors (ACEI) in experimental aortic stenosis (AS), and intravenous nitroprusside …

Aims Left ventricular pressure overload is associated with activation of the cardiac renin–
angiotensin system, which may contribute to myocardial fibrosis and worse clinical …

Background In patients with severe aortic stenosis (AS), treatment with angiotensin-
converting enzyme inhibitors has previously been considered contraindicated. However …

Objectives: The aim of this study was to investigate the effect of renin-angiotensin system
blockade on outcomes in patients with aortic regurgitation (AR). Background: Angiotensin …

Objective: To determine the effects of angiotensin converting enzyme (ACE) inhibitors in
hypertensive patients with aortic valve stenosis (AS). Design: Observational, drug …

Abstract Background The American College of Cardiology/American Heart Association
guidelines recommend the assessment and grading of severity of aortic stenosis (AS) as …