[HTML][HTML] Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management
PS Rawat, A Jaiswal, A Khurana, JS Bhatti… - Biomedicine & …, 2021 - Elsevier
Doxorubicin (Dox) is a secondary metabolite of the mutated strain of Streptomyces peucetius
var. Caesius and belongs to the anthracyclines family. The anti-cancer activity of Dox is …
var. Caesius and belongs to the anthracyclines family. The anti-cancer activity of Dox is …
Molecular mechanism of doxorubicin-induced cardiomyopathy–An update
Doxorubicin is utilized for anti-neoplastic treatment for several decades. The utility of this
drug is limited due to its side effects. Generally, doxorubicin toxicity is originated from the …
drug is limited due to its side effects. Generally, doxorubicin toxicity is originated from the …
Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation
NF Sangweni, K Gabuza, B Huisamen, L Mabasa… - Archives of …, 2022 - Springer
A breakthrough in oncology research was the discovery of doxorubicin (Dox) in the 1960's.
Unlike other chemotherapy drugs, Dox was determined to have a greater therapeutic index …
Unlike other chemotherapy drugs, Dox was determined to have a greater therapeutic index …
Insights into doxorubicin-induced cardiotoxicity: molecular mechanisms, preventive strategies, and early monitoring
Doxorubicin (DOX) is one of the most effective anticancer drugs to treat various forms of
cancers; however, its therapeutic utility is severely limited by its associated cardiotoxicity …
cancers; however, its therapeutic utility is severely limited by its associated cardiotoxicity …
[HTML][HTML] Underlying the mechanisms of doxorubicin-induced acute cardiotoxicity: oxidative stress and cell death
CY Kong, Z Guo, P Song, X Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Cancer is a destructive disease that causes high levels of morbidity and mortality.
Doxorubicin (DOX) is a highly efficient antineoplastic chemotherapeutic drug, but its use …
Doxorubicin (DOX) is a highly efficient antineoplastic chemotherapeutic drug, but its use …
Recent progress in doxorubicin-induced cardiotoxicity and protective potential of natural products
Background As an anthracycline antibiotic, doxorubicin (DOX) is one of the most potent and
widely used chemotherapeutic agents for various types of solid tumors. Unfortunately …
widely used chemotherapeutic agents for various types of solid tumors. Unfortunately …
[PDF][PDF] Molecular mechanisms of cardiotoxicity: a review on major side-effect of doxorubicin
Doxorubicin is among the most widely used drugs for the treatment of both adult and child
cancers. Doxorubicin is the major cause of chemotherapy-induced cardiotoxicity that is dose …
cancers. Doxorubicin is the major cause of chemotherapy-induced cardiotoxicity that is dose …
Doxorubicin-induced cardiotoxicity: causative factors and possible interventions
IC Jones, CR Dass - Journal of Pharmacy and Pharmacology, 2022 - academic.oup.com
Abstract Objectives Doxorubicin (Dox) belongs to the anthracycline drug classification and is
a widely administered chemotherapeutic. However, Dox use in therapy is limited by its …
a widely administered chemotherapeutic. However, Dox use in therapy is limited by its …
[HTML][HTML] Research progress of therapeutic drugs for doxorubicin-induced cardiomyopathy
Y Chen, S Shi, Y Dai - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Doxorubicin (DOX), as a kind of chemotherapy agent with remarkable therapeutic effect, can
be used to treat diverse malignant tumors clinically. Dose-dependent cardiotoxicity is the …
be used to treat diverse malignant tumors clinically. Dose-dependent cardiotoxicity is the …
Doxorubicin-induced cardiotoxicity: an overview on pre-clinical therapeutic approaches
Doxorubicin is an effective chemotherapeutic agent prescribed to treat solid tumors (eg,
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …