Mechanism and role of mitophagy in the development of severe infection

L Ma, T Han, Y Zhan - Cell Death Discovery, 2024 - nature.com
Mitochondria produce adenosine triphosphate and potentially contribute to proinflammatory
responses and cell death. Mitophagy, as a conservative phenomenon, scavenges waste …

The role of mitophagy in pulmonary sepsis

M Mohsin, G Tabassum, S Ahmad, S Ali, MA Syed - Mitochondrion, 2021 - Elsevier
Sepsis is a systemic inflammatory disease with an unacceptably high mortality rate caused
by an infection or trauma that involves both innate and adaptive immune systems …

[HTML][HTML] Mitophagy and innate immunity in infection

DH Cho, JK Kim, EK Jo - Molecules and cells, 2020 - Elsevier
Mitochondria have several quality control mechanisms by which they maintain cellular
homeostasis and ensure that the molecular machinery is protected from stress. Mitophagy …

Mechanism of mitophagy and its role in sepsis induced organ dysfunction: a review

C Zhu, R Yao, L Li, P Li, J Xie, J Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
Autophagy, an evolutionarily conserved process, plays an important role in maintaining
cellular homeostasis under physiological and pathophysiological conditions. It is widely …

[HTML][HTML] Inhibition of mitophagy drives macrophage activation and antibacterial defense during sepsis

D Patoli, F Mignotte, V Deckert… - The Journal of …, 2020 - Am Soc Clin Investig
Mitochondria have emerged as key actors of innate and adaptive immunity. Mitophagy has a
pivotal role in cell homeostasis, but its contribution to macrophage functions and host …

The mitophagy pathway and its implications in human diseases

S Wang, H Long, L Hou, B Feng, Z Ma, Y Wu… - Signal transduction and …, 2023 - nature.com
Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

The role of mitophagy in innate immune responses triggered by mitochondrial stress

Y Song, Y Zhou, X Zhou - Cell Communication and signaling, 2020 - Springer
Mitochondria are important cellular organelles involved in many different functions, from
energy generation and fatty acid oxidation to cell death regulation and immune responses …

Emerging role of mitophagy in inflammatory diseases: cellular and molecular episodes

MA AA, S Ameenudeen, A Kumar… - Current …, 2020 - ingentaconnect.com
Mitochondria are the crucial regulators for the major source of ATP for different cellular
events. Due to damage episodes, mitochondria have been established for a plethora …

To eat or not to eat mitochondria? How do host cells cope with mitophagy upon bacterial infection?

J Verbeke, X De Bolle, T Arnould - Plos Pathogens, 2023 - journals.plos.org
Mitochondria fulfil a plethora of cellular functions ranging from energy production to
regulation of inflammation and cell death control. The fundamental role of mitochondria …

Keeping the immune system in check: a role for mitophagy

M Lazarou - Immunology and cell biology, 2015 - Wiley Online Library
Mitochondria play a central role in many facets of cellular function including energy
production, control of cell death and immune signaling. Breakdown of any of these pathways …