DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation

J Cadet, JR Wagner - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
Emphasis has been placed in this article dedicated to DNA damage on recent aspects of the
formation and measurement of oxidatively generated damage in cellular DNA in order to …

Effects of UV and visible radiation on DNA-final base damage.

J Cadet, M Berger, T Douki, B Morin, S Raoul… - Biological …, 1997 - europepmc.org
Several mechanisms are likely to be involved in the solar radiation-mediated modifications
of cellular DNA. Direct excitation of DNA bases by the UVB component (290-320 nm) of …

Oxidatively Generated Damage to Cellular DNA by UVB and UVA Radiation,

J Cadet, T Douki, JL Ravanat - Photochemistry and …, 2015 - Wiley Online Library
This review article focuses on a critical survey of the main available information on the UVB
and UVA oxidative reactions to cellular DNA as the result of direct interactions of UV …

Oxidative damage to DNA: formation, measurement, and biological significance

J Cadet, M Berger, T Douki, JL Ravanat - … of Reactive Oxygens, NO, CO, II, 2005 - Springer
Deoxyribonucleic acid (DNA) appears to be a critical cellular target for the biological effects
(cellular lethality, mutagenesis, carcinogenesis, and ageing) of oxidation processes …

Radiation-induced DNA damage: formation, measurement, and biochemical features

J Cadet, S Bellon, T Douki, S Frelon… - Journal of …, 2004 - dl.begellhouse.com
Most of the reactions induced by· OH radicals (indirect effects) and by one-electron oxidation
(direct effects) as the result of exposure to ionizing radiation may be described for the four …

UVA-induced damage to DNA and proteins: direct versus indirect photochemical processes

PM Girard, S Francesconi, M Pozzebon… - Journal of Physics …, 2011 - iopscience.iop.org
UVA has long been known for generating an oxidative stress in cells. In this paper we review
the different types of DNA damage induced by UVA, ie strand breaks, bipyrimidine …

Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells

J Cadet, T Douki, JL Ravanat - Accounts of chemical research, 2008 - ACS Publications
Nuclear DNA and other molecules in living systems are continuously exposed to
endogenously generated oxygen species. Such species range from the unreactive …

Detecting DNA damage

J Cadet, M Weinfeld - Analytical chemistry, 1993 - ACS Publications
The purine and pyrimidine bases in DNA are critical cellular targets of UV light and various
oxidizing agents and processes, including ion-izing radiation, photoexcited dyes, antibiotics …

Ultraviolet radiation-mediated damage to cellular DNA

J Cadet, E Sage, T Douki - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
Emphasis is placed in this review article on recent aspects of the photochemistry of cellular
DNA in which both the UVB and UVA components of solar radiation are implicated …

Wavelength dependence of oxidative DNA damage induced by UV and visible light.

C Kielbassa, L Roza, B Epe - Carcinogenesis, 1997 - academic.oup.com
DNA damage induced by UV radiation and visible light (290-500 nm) in AS52 Chinese
hamster cells was analysed by an alkaline elution assay with specific repair endonucleases …