A nanoantidote alleviates glioblastoma chemotoxicity without efficacy compromise

M Tian, R Xing, J Guan, B Yang, X Zhao, J Yang… - Nano Letters, 2021 - ACS Publications
Cancer patients suffer from the toxicity of chemotherapy. Antidote, given as a remedy limiting
poison, is an effective way to counteract toxicity. However, few antidotes abrogate …

Nanomedicine facilitated cell signaling blockade: difficulties and strategies to overcome glioblastoma

M Habeeb, HT Vengateswaran, HW You… - Journal of Materials …, 2024 - pubs.rsc.org
Glioblastoma (GBM) is a highly aggressive and lethal type of brain tumor with complex and
diverse molecular signaling pathways involved that are in its development and progression …

Deciphering nanoparticle trafficking into glioblastomas uncovers an augmented antitumor effect of metronomic chemotherapy

MJY Ang, J Yoon, M Zhou, HL Wei, YY Goh… - Advanced …, 2022 - Wiley Online Library
Nanoparticles have been explored in glioblastomas as they can traverse the blood–brain
barrier and target glioblastoma selectively. However, direct observation of nanoparticle …

Strategies for advancing cancer nanomedicine

VP Chauhan, RK Jain - Nature materials, 2013 - nature.com
Cancer nanomedicines approved so far minimize toxicity, but their efficacy is often limited by
physiological barriers posed by the tumour microenvironment. Here, we discuss how these …

How Nanotherapeutic Platforms Play a Key Role in Glioma? A Comprehensive Review of Literature

Y Yang, N Cheng, Q Luo, N Shao, X Ma… - International Journal …, 2023 - Taylor & Francis
Glioblastoma (GBM), a highly aggressive form of brain cancer, is considered one of the
deadliest cancers, and even with the most advanced medical treatments, most affected …

Glioma nanomedicine: Design, fabrication and theranostic application

D Wu, J Zhao, T Xu, H Xiang, B Zhao, L Gao… - Coordination Chemistry …, 2024 - Elsevier
As primary intracranial tumors of the central nervous system (CNS), gliomas pose formidable
challenges in the field of oncology due to their aggressiveness, poor prognosis, high risk of …

[HTML][HTML] Glioblastoma multiforme selective nanomedicines for improved anti-cancer treatments

JT Duskey, A Rinaldi, I Ottonelli, R Caraffi… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma Multiforme (GBM) is a devastating disease with a low survival rate and few
efficacious treatment options. The fast growth, late diagnostics, and off-target toxicity of …

Glioblastoma chemotherapeutic agents used in the clinical setting and in clinical trials: Nanomedicine approaches to improve their efficacy

J Aparicio-Blanco, L Sanz-Arriazu, R Lorenzoni… - International Journal of …, 2020 - Elsevier
Even though substantial advances in understanding glioma pathogenesis have prompted a
more rational design of potential therapeutic strategies, glioblastoma multiforme remains an …

[HTML][HTML] Cancer nanomedicine: emerging strategies and therapeutic potentials

M Xu, X Han, H Xiong, Y Gao, B Xu, G Zhu, J Li - Molecules, 2023 - mdpi.com
Cancer continues to pose a severe threat to global health, making pursuing effective
treatments more critical than ever. Traditional therapies, although pivotal in managing …

Nanostructures for cancer therapy: From targeting to selective toxicology

GM Vlasceanu, L Victor, H Maricica, T Raluca… - … for Cancer Therapy, 2017 - Elsevier
Cancer treatment has dramatically evolved as understanding of the underlying biological
process has increased. As new treatments are developed and modified we expect increased …