A nanoantidote alleviates glioblastoma chemotoxicity without efficacy compromise
Cancer patients suffer from the toxicity of chemotherapy. Antidote, given as a remedy limiting
poison, is an effective way to counteract toxicity. However, few antidotes abrogate …
poison, is an effective way to counteract toxicity. However, few antidotes abrogate …
Nanomedicine facilitated cell signaling blockade: difficulties and strategies to overcome glioblastoma
Glioblastoma (GBM) is a highly aggressive and lethal type of brain tumor with complex and
diverse molecular signaling pathways involved that are in its development and progression …
diverse molecular signaling pathways involved that are in its development and progression …
Deciphering nanoparticle trafficking into glioblastomas uncovers an augmented antitumor effect of metronomic chemotherapy
MJY Ang, J Yoon, M Zhou, HL Wei, YY Goh… - Advanced …, 2022 - Wiley Online Library
Nanoparticles have been explored in glioblastomas as they can traverse the blood–brain
barrier and target glioblastoma selectively. However, direct observation of nanoparticle …
barrier and target glioblastoma selectively. However, direct observation of nanoparticle …
Strategies for advancing cancer nanomedicine
VP Chauhan, RK Jain - Nature materials, 2013 - nature.com
Cancer nanomedicines approved so far minimize toxicity, but their efficacy is often limited by
physiological barriers posed by the tumour microenvironment. Here, we discuss how these …
physiological barriers posed by the tumour microenvironment. Here, we discuss how these …
How Nanotherapeutic Platforms Play a Key Role in Glioma? A Comprehensive Review of Literature
Y Yang, N Cheng, Q Luo, N Shao, X Ma… - International Journal …, 2023 - Taylor & Francis
Glioblastoma (GBM), a highly aggressive form of brain cancer, is considered one of the
deadliest cancers, and even with the most advanced medical treatments, most affected …
deadliest cancers, and even with the most advanced medical treatments, most affected …
Glioma nanomedicine: Design, fabrication and theranostic application
As primary intracranial tumors of the central nervous system (CNS), gliomas pose formidable
challenges in the field of oncology due to their aggressiveness, poor prognosis, high risk of …
challenges in the field of oncology due to their aggressiveness, poor prognosis, high risk of …
[HTML][HTML] Glioblastoma multiforme selective nanomedicines for improved anti-cancer treatments
Glioblastoma Multiforme (GBM) is a devastating disease with a low survival rate and few
efficacious treatment options. The fast growth, late diagnostics, and off-target toxicity of …
efficacious treatment options. The fast growth, late diagnostics, and off-target toxicity of …
Glioblastoma chemotherapeutic agents used in the clinical setting and in clinical trials: Nanomedicine approaches to improve their efficacy
J Aparicio-Blanco, L Sanz-Arriazu, R Lorenzoni… - International Journal of …, 2020 - Elsevier
Even though substantial advances in understanding glioma pathogenesis have prompted a
more rational design of potential therapeutic strategies, glioblastoma multiforme remains an …
more rational design of potential therapeutic strategies, glioblastoma multiforme remains an …
[HTML][HTML] Cancer nanomedicine: emerging strategies and therapeutic potentials
M Xu, X Han, H Xiong, Y Gao, B Xu, G Zhu, J Li - Molecules, 2023 - mdpi.com
Cancer continues to pose a severe threat to global health, making pursuing effective
treatments more critical than ever. Traditional therapies, although pivotal in managing …
treatments more critical than ever. Traditional therapies, although pivotal in managing …
Nanostructures for cancer therapy: From targeting to selective toxicology
GM Vlasceanu, L Victor, H Maricica, T Raluca… - … for Cancer Therapy, 2017 - Elsevier
Cancer treatment has dramatically evolved as understanding of the underlying biological
process has increased. As new treatments are developed and modified we expect increased …
process has increased. As new treatments are developed and modified we expect increased …