[HTML][HTML] Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation
Hepatocellular adenomas (HCA) are benign liver tumors predominantly developed in
women using oral contraceptives. Here, exome sequencing identified recurrent somatic FRK …
women using oral contraceptives. Here, exome sequencing identified recurrent somatic FRK …
Hepatocellular benign tumors—from molecular classification to personalized clinical care
JC Nault, P Bioulac–Sage, J Zucman–Rossi - Gastroenterology, 2013 - Elsevier
Focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) are benign
hepatocellular tumors that develop most frequently in women without cirrhosis. Genomic …
hepatocellular tumors that develop most frequently in women without cirrhosis. Genomic …
[HTML][HTML] Cell cycle–related kinase is a direct androgen receptor–regulated gene that drives β-catenin/T cell factor–dependent hepatocarcinogenesis
H Feng, ASL Cheng, DP Tsang, MS Li… - The Journal of …, 2011 - Am Soc Clin Investig
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. It is more
prevalent in men than women. Related to this, recent genetic studies have revealed a causal …
prevalent in men than women. Related to this, recent genetic studies have revealed a causal …
[PDF][PDF] Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
S Boyault, DS Rickman, A De Reyniès… - …, 2007 - Wiley Online Library
Hepatocellular carcinomas (HCCs) are a heterogeneous group of tumors that differ in risk
factors and genetic alterations. We further investigated transcriptome‐genotype‐phenotype …
factors and genetic alterations. We further investigated transcriptome‐genotype‐phenotype …
Analysis of genomes and transcriptomes of hepatocellular carcinomas identifies mutations and gene expression changes in the transforming growth factor-β pathway
Background & Aims Development of hepatocellular carcinoma (HCC) is associated with
alterations in the transforming growth factor-beta (TGF-β) signaling pathway, which …
alterations in the transforming growth factor-beta (TGF-β) signaling pathway, which …
Molecular classification of hepatocellular adenoma associates with risk factors, bleeding, and malignant transformation
JC Nault, G Couchy, C Balabaud, G Morcrette… - Gastroenterology, 2017 - Elsevier
Background & Aims Hepatocellular adenomas (HCAs) are benign liver tumors that can be
assigned to molecular subtypes based on inactivating mutations in hepatocyte nuclear factor …
assigned to molecular subtypes based on inactivating mutations in hepatocyte nuclear factor …
Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma
S Rebouissou, P Bioulac-Sage, J Zucman-Rossi - Journal of hepatology, 2008 - Elsevier
Focal nodular hyperplasia (FNH) and hepatocellular adenomas (HCAs) are benign tumors
that occur in otherwise normal liver parenchyma. FNH is considered to be the result of a …
that occur in otherwise normal liver parenchyma. FNH is considered to be the result of a …
[HTML][HTML] Molecular genetics of hepatocellular neoplasia
S Jain, S Singhal, P Lee, R Xu - American journal of translational …, 2010 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the sixth most common malignancy and the third leading
cause of cancer deaths worldwide. Proper classification and early identification of HCC and …
cause of cancer deaths worldwide. Proper classification and early identification of HCC and …
The genomic landscape of hepatoblastoma and their progenies with HCC-like features
M Eichenmüller, F Trippel, M Kreuder, A Beck… - Journal of …, 2014 - Elsevier
Background & Aims Hepatoblastoma (HB) is the most common childhood liver cancer and
occasionally presents with histological and clinical features reminiscent of hepatocellular …
occasionally presents with histological and clinical features reminiscent of hepatocellular …
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
Genomic analyses promise to improve tumor characterization to optimize personalized
treatment for patients with hepatocellular carcinoma (HCC). Exome sequencing analysis of …
treatment for patients with hepatocellular carcinoma (HCC). Exome sequencing analysis of …
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