Engineered spindles of little molecules around electrospun nanofibers for biphasic drug release

H He, M Wu, J Zhu, Y Yang, R Ge, DG Yu - Advanced Fiber Materials, 2021 - Springer
Biphasic drug release is a popular advanced drug controlled release profile that has been
drawing increasing attention from many fields. Electrospun nanofibers and their derivatives …

Electrospun drug-loaded core–sheath PVP/zein nanofibers for biphasic drug release

YN Jiang, HY Mo, DG Yu - International journal of pharmaceutics, 2012 - Elsevier
Core–sheath nanofibers prepared using coaxial electrospinning were investigated for
providing biphasic drug release profiles. With ketoprofen (KET) as the model drug …

Electrospun biphasic drug release polyvinylpyrrolidone/ethyl cellulose core/sheath nanofibers

DG Yu, X Wang, XY Li, W Chian, Y Li, YZ Liao - Acta Biomaterialia, 2013 - Elsevier
The capability of core/sheath nanofibers prepared using coaxial electrospinning to provide
adjustable biphasic drug release was investigated. Using ketoprofen (KET) as the model …

Electrospun triaxial nanofibers with middle blank cellulose acetate layers for accurate dual-stage drug release

Y Yang, S Chang, Y Bai, Y Du, DG Yu - Carbohydrate polymers, 2020 - Elsevier
The combination of complex nanostructures with carbohydrate polymers can provide a
strong platform for promoting the development of novel drug delivery systems. In this study …

Dual drug release electrospun core-shell nanofibers with tunable dose in the second phase

W Qian, DG Yu, Y Li, YZ Liao, X Wang… - International journal of …, 2014 - mdpi.com
This study reports a new type of drug-loaded core-shell nanofibers capable of providing dual
controlled release with tunable dose in the second phase. The core-shell nanofibers were …

Electrospun fibers with blank surface and inner drug gradient for improving sustained release

M Wang, RL Ge, F Zhang, DG Yu, ZP Liu, X Li… - Biomaterials …, 2023 - Elsevier
New engineering methods and advanced strategies are highly desired for creating novel
drug sustained release nanomaterials. In this study, a trilayer concentric spinneret was …

Elaborate design of shell component for manipulating the sustained release behavior from core–shell nanofibres

Y Liu, X Chen, Y Gao, DG Yu, P Liu - Journal of Nanobiotechnology, 2022 - Springer
Background The diversified combination of nanostructure and material has received
considerable attention from researchers to exploit advanced functional materials. In drug …

Tunable drug release from nanofibers coated with blank cellulose acetate layers fabricated using tri-axial electrospinning

Y Yang, W Li, DG Yu, G Wang, GR Williams… - Carbohydrate …, 2019 - Elsevier
In this study, novel core-shell nanostructures were fabricated through a modified triaxial
electrospinning process. These comprised a drug-protein nanocomposite coated with a thin …

Biphasic drug release from electrospun structures

J Zhou, P Wang, DG Yu, Y Zhu - Expert Opinion on Drug Delivery, 2023 - Taylor & Francis
Introduction Biphasic release, as a special drug-modified release profile that combines
immediate and sustained release, allows fast therapeutic action and retains blood drug …

Tunable zero-order drug delivery systems created by modified triaxial electrospinning

X Liu, Y Yang, DG Yu, MJ Zhu, M Zhao… - Chemical Engineering …, 2019 - Elsevier
The ability to accurately control a material's structure, and in turn its functional performance,
is of crucial importance for potential applications. In this study, a new modified triaxial …