Systems biology and multi-omics integration: viewpoints from the metabolomics research community

FR Pinu, DJ Beale, AM Paten, K Kouremenos… - Metabolites, 2019 - mdpi.com
The use of multiple omics techniques (ie, genomics, transcriptomics, proteomics, and
metabolomics) is becoming increasingly popular in all facets of life science. Omics …

Approaches to integrating metabolomics and multi-omics data: a primer

T Jendoubi - Metabolites, 2021 - mdpi.com
Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

Multi-omics integration in biomedical research–A metabolomics-centric review

MA Wörheide, J Krumsiek, G Kastenmüller… - Analytica chimica …, 2021 - Elsevier
Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …

Analysis of metabolomic data: tools, current strategies and future challenges for omics data integration

A Cambiaghi, M Ferrario… - Briefings in bioinformatics, 2017 - academic.oup.com
Metabolomics is a rapidly growing field consisting of the analysis of a large number of
metabolites at a system scale. The two major goals of metabolomics are the identification of …

Metabox: A toolbox for metabolomic data analysis, interpretation and integrative exploration

K Wanichthanarak, S Fan, D Grapov, DK Barupal… - PloS one, 2017 - journals.plos.org
Similar to genomic and proteomic platforms, metabolomic data acquisition and analysis is
becoming a routine approach for investigating biological systems. However, computational …

[HTML][HTML] Metabolomics of a superorganism

R Goodacre - The Journal of nutrition, 2007 - Elsevier
The human can be thought of as a human-microbe hybrid, and the health of this
superorganism will be affected by intrinsic properties such as human genetics, diurnal …

Metabolomics--a new exciting field within the" omics" sciences.

K Dettmer, BD Hammock - Environmental health perspectives, 2004 - ehp.niehs.nih.gov
Although metabolomics is still in an early evolutionary stage, we can expect to see exciting
new developments in the near future. As more quantitative metabolomic databases evolve …

Establishing reporting standards for metabolomic and metabonomic studies: a call for participation

O Fiehn, B Kristal, BV Ommen, LW Sumner… - Omics: a journal of …, 2006 - liebertpub.com
Metabolite concentrations in cellular systems are very much dependent on the physiological,
environmental, and genetic status of an organism and are regarded as the ultimate result of …

Metabolomics reviewed: a new “omics” platform technology for systems biology and implications for natural products research

S Rochfort - Journal of natural products, 2005 - ACS Publications
Metabolomics is the study of global metabolite profiles in a system (cell, tissue, or organism)
under a given set of conditions. The analysis of the metabolome is particularly challenging …

Metabolomics and multi-omics integration: a survey of computational methods and resources

T Eicher, G Kinnebrew, A Patt, K Spencer, K Ying, Q Ma… - Metabolites, 2020 - mdpi.com
As researchers are increasingly able to collect data on a large scale from multiple clinical
and omics modalities, multi-omics integration is becoming a critical component of …