Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review

P Liu, B Jill, H Lu - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

MRI mapping of cerebrovascular reactivity via gas inhalation challenges

H Lu, P Liu, U Yezhuvath, Y Cheng, O Marshall… - JoVE (Journal of …, 2014 - jove.com
The brain is a spatially heterogeneous and temporally dynamic organ, with different regions
requiring different amount of blood supply at different time. Therefore, the ability of the blood …

Cerebrovascular reactivity mapping without gas challenges

P Liu, Y Li, M Pinho, DC Park, BG Welch, H Lu - Neuroimage, 2017 - Elsevier
Cerebrovascular reactivity (CVR), the ability of cerebral vessels to dilate or constrict, has
been shown to provide valuable information in the diagnosis and treatment evaluation of …

Cerebrovascular reactivity mapping without gas challenges: a methodological guide

J Pinto, MG Bright, DP Bulte, P Figueiredo - Frontiers in Physiology, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) is defined as the ability of vessels to alter their caliber in
response to vasoactive factors, by means of dilating or constricting, in order to increase or …

On the assessment of cerebrovascular reactivity using hypercapnia BOLD MRI

US Yezhuvath, K Lewis‐Amezcua… - NMR in Biomedicine …, 2009 - Wiley Online Library
Cerebrovascular reactivity (CVR) reflects the capacity of blood vessels to dilate and is an
important marker for brain vascular reserve. It may provide a useful addition to the traditional …

[HTML][HTML] Respiratory challenge MRI: practical aspects

FC Moreton, KA Dani, C Goutcher, K O'Hare… - NeuroImage: Clinical, 2016 - Elsevier
Respiratory challenge MRI is the modification of arterial oxygen (PaO 2) and/or carbon
dioxide (PaCO 2) concentration to induce a change in cerebral function or metabolism which …

Assessment of cerebrovascular reactivity with functional magnetic resonance imaging: comparison of CO2 and breath holding

A Kastrup, G Krüger, T Neumann-Haefelin… - Magnetic resonance …, 2001 - Elsevier
Cerebral blood flow (CBF) and oxygenation changes following both a simple breath holding
test (BHT) and a CO2 challenge can be detected with functional magnetic resonance …

Blood‐oxygen level dependent MRI measures of cerebrovascular reactivity using a controlled respiratory challenge: reproducibility and gender differences

A Kassner, JD Winter, J Poublanc… - Journal of Magnetic …, 2010 - Wiley Online Library
Purpose: To evaluate the reproducibility and gender differences in cerebrovascular reactivity
(CVR) measurements obtained using the blood‐oxygen level dependent (BOLD) response …

CO2 Blood Oxygen Level–dependent MR Mapping of Cerebrovascular Reserve in a Clinical Population: Safety, Tolerability, and Technical Feasibility

VR Spano, DM Mandell, J Poublanc, K Sam… - Radiology, 2013 - pubs.rsna.org
Purpose To evaluate the safety, tolerability, and technical feasibility of mapping
cerebrovascular reactivity (CVR) in a clinical population by using a precise prospectively …

Investigating the non-linearity of the BOLD cerebrovascular reactivity response to targeted hypo/hypercapnia at 7 T

AA Bhogal, JCW Siero, JA Fisher, M Froeling, P Luijten… - Neuroimage, 2014 - Elsevier
Cerebrovascular reactivity (CVR) is a mechanism responsible for maintaining stable
perfusion pressure within the brain via smooth muscle mediated modulations of vascular …