The cAMP-dependent protein kinase (PKA) system represents a primary cell-signaling
pathway throughout systems and across species. PKA facilitates the actions of hormones …

Both direct and indirect evidence demonstrate a central role for the cAMP-dependent protein
kinase (PKA) signaling pathway in the regulation of energy balance and metabolism across …

Many of the fundamental concepts of signal transduction and kinase activity are attributed to
the discovery and crystallization of cAMP-dependent protein kinase, or protein kinase A …

In mammals, cyclic adenosine monophosphate (cAMP) is an intracellular second
messenger that is usually elicited by binding of hormones and neurotransmitters to G protein …

The evolutionarily conserved serine/threonine kinase, AMP‐activated protein kinase
(AMPK), functions as a cellular fuel gauge that regulates metabolic pathways in glucose and …

Mitogen‐activated protein kinase (MAPK) signalling occurs in response to almost any
change in the extracellular or intracellular milieu that affects the metabolism of the cell …

The major regulator of lipolysis in white adipocytes and brown adipocytes is cAMP and the
actions of cAMP are mediated by protein kinase A (PKA). Multiple subunits of PKA, including …

Pyruvate kinase (PK) and the phosphoenolpyruvate (PEP) cycle play key roles in nutrient-
stimulated K ATP channel closure and insulin secretion. To identify the PK isoforms …

Protein kinase A (PKA) signaling, in “classic” endocrine cell functioning, is known to mediate
cAMP effects, generated through adenylate cyclase as a response to the activation of G …

Taskén, Kjetil, and Einar Martin Aandahl. Localized Effects of cAMP Mediated by Distinct
Routes of Protein Kinase A. Physiol Rev 84: 137–167, 2004; 10.1152/physrev. 00021.2003 …