Oikonomou et al1 report an association between alcohol consumption and ascending
thoracic aorta dilatation in their valuable study. We aim to contribute to their article by …

Angiotensin (Ang) II infusion increases atherosclerosis and leads to the formation of
abdominal aortic aneurysms in apolipoprotein E-deficient (ApoE−/−) mice. Conversely …

BACKGROUND: Valvular aortic stenosis (AS) is not an infrequent condition in the aged
population. Activation of renin-angiotensin system (RAS) is presumed to be involved in the …

1 We have demonstrated previously that infusion of angiotensin II (AngII) into hyperlipidemic
mice augments atherosclerosis and results in the formation of abdominal aortic aneurysms …

Aortic diameter and progression to thoracic aortic aneurysm are influenced by several
factors. In this study, we investigated the association of alcohol consumption with aortic root …

Infusion of ANG II in hyperlipidemic mice augments atherosclerosis and causes formation of
abdominal aortic aneurysms (AAAs). The purpose of this study was to define the contribution …

Objective—Abdominal aortic aneurysm (AAA) is a life-threatening disease affecting almost
10% of the population over age 65. Generation of AAAs by infusion of angiotensin (Ang) II in …

The apolipoprotein E-deficient (apoE-/-) mouse model has advanced our understanding of
cardiovascular disease mechanisms and experimental therapeutics. This spontaneous …

Angiotensin (Ang) II exerts direct effects on the arterial wall to influence atherosclerosis and
aneurysm development with the induction of vascular inflammation. Therefore, we examined …

Abdominal and Thoracic aortic aneurysmal diseases are devastating with a high risk of
rupture that frequently leads to death. Regardless of significant improvements in the …