Plasma miR-34a-5p and miR-545-3p as early biomarkers of Alzheimer's disease: potential and limitations

M Cosín-Tomás, A Antonell, A Lladó, D Alcolea… - Molecular …, 2017 - Springer
Plasma microRNAs (miRNAs) have been proposed as potential biomarkers in Alzheimer's
disease (AD). Here, we explored their use as early sensors of the preclinical phase of the …

MicroRNAs in plasma and cerebrospinal fluid as potential markers for Alzheimer's disease

T Kiko, K Nakagawa, T Tsuduki… - Journal of …, 2014 - content.iospress.com
The development of Alzheimer's disease (AD) biomarkers remains an unmet challenge, and
new approaches that can improve current AD biomarker strategies are needed. Recent …

MicroRNA-29a is a candidate biomarker for Alzheimer's disease in cell-free cerebrospinal fluid

M Müller, L Jäkel, IB Bruinsma, JA Claassen… - Molecular …, 2016 - Springer
The identification of reliable biomarkers for Alzheimer's disease (AD) remains challenging.
Recently, abnormal levels of microRNAs (miRNAs) miR-27a, miR-29a, miR-29b, and miR …

Circulating miRNAs as potential biomarkers in Alzheimer's disease

D Galimberti, C Villa, C Fenoglio… - Journal of …, 2014 - content.iospress.com
Several micro (mi) RNA are deregulated in brain, cerebrospinal fluid (CSF), and
serum/plasma from patients with Alzheimer's disease (AD). The aim of the study was to …

Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer's disease

N Hara, M Kikuchi, A Miyashita, H Hatsuta… - Acta neuropathologica …, 2017 - Springer
MicroRNAs (miRNAs) are attractive molecules to utilize as one of the blood-based
biomarkers for neurodegenerative disorders such as Alzheimer's disease (AD) because …

Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer's disease

D Siedlecki-Wullich, J Català-Solsona… - Alzheimer's research & …, 2019 - Springer
Background Several evidences suggest that failure of synaptic function occurs at preclinical
stages of Alzheimer's disease (AD) preceding neuronal loss and the classical AD …

Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease

H Geekiyanage, GA Jicha, PT Nelson, C Chan - Experimental neurology, 2012 - Elsevier
There is an urgent need to identify non-invasive biomarkers for the detection of sporadic
Alzheimer's disease (AD). We previously studied microRNAs (miRNAs) in AD autopsy brain …

Circulating miR-125b as a biomarker of Alzheimer's disease

L Tan, JT Yu, QY Liu, MS Tan, W Zhang, N Hu… - Journal of the …, 2014 - Elsevier
Background MicroRNAs (miRNAs) are endogenous small RNAs of 21–25 nucleotides that
post-transcriptionally regulate gene expressions. Recently, circulating miRNAs have been …

Plasma microRNAs as potential biomarkers in early Alzheimer disease expression

C Peña-Bautista, A Tarazona-Sánchez… - Scientific Reports, 2022 - nature.com
The microRNAs (miRNAs) are potential biomarkers for complex pathologies due to their
involvement in the regulation of several pathways. Alzheimer Disease (AD) requires new …

MicroRNA-455-3p as a potential peripheral biomarker for Alzheimer's disease

S Kumar, M Vijayan, PH Reddy - Human molecular genetics, 2017 - academic.oup.com
The purpose of our study was to identify microRNAs (miRNAs) as early detectable
peripheral biomarkers in Alzheimer's disease (AD). To achieve our objective, we assessed …