Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …

Stressor exposure during early life has the potential to increase an individual's susceptibility
to a number of neuropsychiatric conditions such as mood and anxiety disorders and …

Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …

Comprehensive clinical studies show that adverse conditions in early life can severely
impact the developing brain and increase vulnerability to mood disorders later in life. During …

Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Risk for neuropsychiatric disorders is complex and includes an individual's internal genetic
endowment and their environmental experiences and exposures. Embryonic development …

The transgenerational epigenetic programming involved in the passage of environmental
exposures to stressful periods from one generation to the next has been examined in human …

Early life adversity is associated with long-term effects on physical and mental health later in
life, but the mechanisms are yet unclear. Epigenetic mechanisms program cell-type-specific …

A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

This review focuses on current research developments in the study of gene by early life
stress (ELS) interactions and depression. ELS refers to aversive experiences during …