Research in many cancers has uncovered changes in metabolic pathways that control
tumour energetics and biosynthesis, so-called metabolic reprogramming. Studies in clear …

Introduction: Clear cell renal cell carcinoma (ccRCC) is a metabolic disease, of which the
incidence rate is increasing worldwide. Renal carcinoma is characterized by mutations in …

Molecular profiling studies of tumor tissue from patients with clear cell renal cell cancer
(ccRCC) have revealed extensive metabolic reprogramming in this disease. Associations …

Kidney cancer, or renal cell carcinoma (RCC), is a disease of increasing incidence that
commonly is seen in the general practice of nephrology. Despite this state of affairs, this …

Clear cell renal cell carcinoma (ccRCC) has a poor prognosis despite novel biological
targeted therapies. Tumor aggressiveness and poor survival may correlate with tumor grade …

Targeting metabolic vulnerabilities has been proposed as a therapeutic strategy in renal cell
carcinoma (RCC). Here, we analyzed the metabolism of patient-derived xenografts …

Recent studies have established that tumors can reprogram the pathways involved in
nutrient uptake and metabolism to withstand the altered biosynthetic, bioenergetics and …

Clear cell renal cell carcinoma (ccRCC) is the most frequent histological kidney cancer
subtype. Over the last decade, significant progress has been made in identifying the genetic …

Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and
metabolic heterogeneity. Here we perform genomic, transcriptomic, proteomic, metabolomic …

Lipid droplet formation is a defining histological feature in clear-cell renal cell carcinoma
(ccRCC) but the underlying mechanisms and importance of this biological behaviour have …