In the last 25 years, a number of animal models, mainly rodents, have been generated with
the goal to mimic cholestatic liver injuries and, thus, to provide in vivo tools to investigate the …

Cholestasis is a frequent clinical condition initiating or complicating chronic liver diseases,
particularly cholangiopathies, where the biliary epithelium is the primary target of the …

The diseases of the intrahepatic biliary tree are a large group of potentially evolutive
congenital and acquired liver disorders affecting both the adult and pediatric populations …

Cholangiocytes, the epithelial cells lining the intrahepatic and extrahepatic bile ducts, are
highly specialized cells residing in a complex anatomic niche where they participate in bile …

Cholangiocytes are the epithelial cells that line the bile ducts. Along the biliary tree, two
different kinds of cholangiocytes exist: small and large cholangiocytes. Each type has …

Cholangiocytes, the cells lining bile ducts, are a heterogenous, highly dynamic population of
epithelial cells. While these cells comprise a small fraction of the total cellular component of …

Cholangiocytes, a small population of cells within the normal liver, have been the focus of a
significant amount of research over the past two decades because of their involvement in …

Cholangiocytes, the epithelial cells lining the bile ducts, are an important subset of liver
cells. They are involved in the modification of bile volume and composition, and respond to …

The intrahepatic bile ducts comprise a complex 3-di-mensional network of conduits within
the liver lined by specialized epithelial cells called cholangiocytes. A major function of …

Cholestatic liver disorders are caused by genetic defects, mechanical aberrations, toxins, or
dysregulations in the immune system that damage the bile ducts and cause accumulation of …