Pharmacoepigenetics of Schizophrenia
C Adanty - 2021 - search.proquest.com
Schizophrenia is a severe psychiatric disorder primarily involving symptoms of psychosis.
Antipsychotic administration is primarily relied upon by clinicians to treat and manage …
Antipsychotic administration is primarily relied upon by clinicians to treat and manage …
Epigenetics for drug discovery: dissecting the effect of high antipsychotic dosage and D2 blockage on peripheral DNA methylation
Introduction The relationship between genetic polymorphisms of antipsychotic drug-
metabolizing agents and drug receptors has been often investigated. DNA methylation is a …
metabolizing agents and drug receptors has been often investigated. DNA methylation is a …
DNA methylation and antipsychotic treatment mechanisms in schizophrenia: Progress and future directions
Antipsychotic response in schizophrenia is a complex, multifactorial trait influenced by
pharmacogenetic factors. With genetic studies thus far providing little biological insight or …
pharmacogenetic factors. With genetic studies thus far providing little biological insight or …
Head-to-head comparison of various antipsychotic agents on genome-wide methylation in schizophrenia
Aim: To explore possible differences in genome-wide methylation between schizophrenia
patients who consume various antipsychotics. Methods: We compared DNA methylation in …
patients who consume various antipsychotics. Methods: We compared DNA methylation in …
Antipsychotic medications and DNA methylation in schizophrenia and bipolar disorder: a systematic review
KJ Burghardt, AS Khoury, Z Msallaty… - … : The Journal of …, 2020 - Wiley Online Library
The pharmacoepigenetics of antipsychotic treatment in severe mental illness is a growing
area of research that aims to understand the interface between antipsychotic treatment and …
area of research that aims to understand the interface between antipsychotic treatment and …
Genome-wide methylation analysis of treatment resistant schizophrenia
V De Luca, Z Chaudhary, N Al-Chalabi, J Qian… - Journal of Neural …, 2023 - Springer
Various studies have investigated the relationship between genetic polymorphisms of
antipsychotic drug-metabolizing agents and drug response. DNA methylation is a form of …
antipsychotic drug-metabolizing agents and drug response. DNA methylation is a form of …
Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset
Even though schizophrenia has a strong hereditary component, departures from simple
genetic transmission are prominent. DNA methylation has emerged as an epigenetic …
genetic transmission are prominent. DNA methylation has emerged as an epigenetic …
DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia
We performed a systematic analysis of blood DNA methylation profiles from 4483
participants from seven independent cohorts identifying differentially methylated positions …
participants from seven independent cohorts identifying differentially methylated positions …
An integrated genetic-epigenetic analysis of schizophrenia: Evidence for Co-localization of genetic associations and differential DNA methylation from a Large meta …
Background Schizophrenia is a severe, highly heritable, neuropsychiatric disorder
characterized by episodic psychosis and altered cognitive function. Despite recent …
characterized by episodic psychosis and altered cognitive function. Despite recent …
DNA methylation in schizophrenia: progress and challenges of epigenetic studies
Schizophrenia is a severe psychiatric disease affecting about 1% of the world's population,
with significant effects on patients and society. Genetic studies have identified several …
with significant effects on patients and society. Genetic studies have identified several …