Endocrine disruptors, epigenetically induced changes, and transgenerational transmission of characters and epigenetic states

C Guerrero-Bosagna, L Valladares - Endocrine-disrupting chemicals …, 2007 - Springer
Developmental epigenetics is a broad phenomenon, which was initially described by
Waddington as “the branch of biology which studies the causal interactions between genes …

Understanding epigenetic effects of endocrine disrupting chemicals: from mechanisms to novel test methods

A Alavian‐Ghavanini, J Rüegg - Basic & clinical pharmacology …, 2018 - Wiley Online Library
Endocrine‐disrupting chemicals (EDC s) are man‐made chemicals that interfere with
hormonal signalling pathways. They are used in, for example, production of common …

Multigenerational and transgenerational effects of endocrine disrupting chemicals: A role for altered epigenetic regulation?

F Xin, M Susiarjo, MS Bartolomei - Seminars in cell & developmental …, 2015 - Elsevier
Increasing evidence has highlighted the critical role of early life environment in shaping the
future health outcomes of an individual. Moreover, recent studies have revealed that early …

The EDCs as epigenetic disruptors: Implications for development and health

MP Herráez, M Lombó, S González-Rojo - … Contaminants and Endocrine …, 2023 - Elsevier
Epigenetics is often defined as the study of mitotically and/or meiotically inherited changes
in gene expression that are not produced by alterations of DNA sequence. Since a few years …

Endocrine disrupters: the new players able to affect the epigenome

L Casati, R Sendra, V Sibilia, F Celotti - Frontiers in cell and …, 2015 - frontiersin.org
Epigenetics represents the way by which the environment is able to program the genome;
there are three main levels of epigenetic control on genome: DNA methylation, post …

Endocrine disruptors: do family lines carry an epigenetic record of previous generations' exposures?

RT Zoeller - Endocrinology, 2006 - academic.oup.com
Endocrine disruptors are generally defined as chemicals in the environment that interfere
with hormone signaling to such an extent that they cause adverse effects (eg Ref. 1). The …

[HTML][HTML] Developmental exposure to endocrine disrupting chemicals alters the epigenome: identification of reprogrammed targets

L Prusinski, A Al-Hendy, Q Yang - Gynecology and obstetrics …, 2016 - ncbi.nlm.nih.gov
Endocrine disruptions induced by environmental toxicants have placed an immense burden
on society to properly diagnose, treat and attempt to alleviate symptoms and disease …

Endocrine disruptor induction of epigenetic transgenerational inheritance of disease

MK Skinner - Molecular and cellular endocrinology, 2014 - Elsevier
Environmental exposures such as toxicants, nutrition and stress have been shown to
promote the epigenetic transgenerational inheritance of disease susceptibility. Endocrine …

Impact of endocrine disruptors upon non-genetic inheritance

D Montjean, AS Neyroud, MG Yefimova… - International Journal of …, 2022 - mdpi.com
Similar to environmental factors, EDCs (endocrine-disrupting chemicals) can influence gene
expression without modifying the DNA sequence. It is commonly accepted that the …

Transgenerational epigenetics of endocrine-disrupting chemicals

RR Dietert - Transgenerational epigenetics, 2014 - Elsevier
The microbiome may play a role in vulnerability to toxicant-induced epigenetic alterations.
One of the most significant categories of toxicants known, the endocrine-disrupting …