For the past century, insulin injections have saved millions of lives, but glycemic instability is
still a persistent challenge for people with diabetes, leading to tremendous morbidity and …

Diabetes mellitus is characterized by the body's inability to control blood glucose levels
within a physiological range due to loss and/or dysfunction of insulin producing beta cells …

Type 1, insulin-dependent, diabetes is one of the more costly chronic diseases of children,
adolescents and adults in Europe and North America. While routine insulin injections …

Treatment of type 1 diabetes with insulin injection is expensive, complicated, and
insufficient. While cadaveric islet transplantations coupled with immunosuppressants can …

Around 400 million people worldwide suffer from diabetes mellitus. The major pathological
event for Type 1 diabetes and advanced Type 2 diabetes is loss or impairment of insulin …

Pancreatic islet transplantation has demonstrated that long-term insulin independence may
be achieved in patients suffering from diabetes mellitus type 1. However, because of limited …

While insulin replacement remains the cornerstone treatment for type I diabetes mellitus
(T1DM), the transplantation of pancreatic islets of Langerhans has the potential to become …

Diabetes is characterized by elevated levels of blood glucose as a result of insufficient
production of insulin from loss or dysfunction of pancreatic islet β‐cells. Here, we review …

Patients with diabetes experience decreased insulin secretion that is linked to a significant
reduction in the number of islet cells. Reversal of diabetes can be achieved through islet …

Replacement of the insulin-producing pancreatic islet β cells represents the ultimate
treatment for type 1 diabetes. Recent advances in islet transplantation underscore the urgent …