Thoracic aortic dissection (TAD) is common but lethal cardiovascular disease with high
mortality. This study aimed to expound whether and how sGC-PRKG1 signaling pathway …

In the present study, the role and molecular mechanism of long noncoding RNA CDKN2B-
AS1 in human thoracic aortic dissection (TAD), a highly lethal cardiovascular disease, was …

Background Phenotypic switching in vascular smooth muscle cells (VSMCs) is involved in
the pathogenesis of aortic dissection (AD). This study aims to explore the potential …

Background: Numerous pieces of evidence have indicated that thoracic aortic dissection
(TAD) is an inflammatory disease. Sphingosine-1-phosphate receptor 2 (S1PR2) signaling …

Thoracic aortic dissection (TAD) is a highly lethal vascular disease characterized by medial
degeneration. Heat shock protein 90 (HSP90) had been proved as a potential target for a …

Aims Acute aortic dissection (AAD) is a life-threatening disease with high morbidity and
mortality. Previous studies have showed that vascular smooth muscle cell (VSMC) …

Background Aortic dissection (AD) is a fatal vascular disease in absence of effective
pharmaceutical therapy. Adenosine monophosphate-activated protein kinase α (AMPKα) …

The vascular smooth muscle cell (VSMC) phenotypic switch is considered to be the key
pathophysiological change in various cardiovascular diseases, such as aortic dissection …

Abstract Background and Aims Stanford type A aortic dissection (AD) is a degenerative
aortic remodelling disease marked by an exceedingly high mortality without effective …

Background: The molecular mechanisms associated with thoracic aortic dissection (TAD)
remain poorly understood. A comprehensive high-throughput sequencing-based analysis of …