Dysregulated macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2
phenotypes underlies impaired cutaneous wound healing. This study reveals Vγ4+ γδ T …

Abstract Monocytes (Mos)/macrophages (Mϕs) orchestrate biological processes critical for
efficient skin wound healing. However, current understanding of skin wound Mo/Mϕ …

Wound healing is a complex and dynamic process that progresses through the distinct
phases of hemostasis, inflammation, proliferation, and remodeling. Both inflammation and re …

Regeneration of skin's barrier function after injury requires temporally coordinated cellular
interactions between multiple cell types. Macrophages are essential inflammatory cells in …

Tissue repair is largely regulated by diverse macrophage populations whose functions are
timing-and context-dependent. The early phase of healing is dominated by pro-inflammatory …

Chronic, nonhealing wounds remain a clinical challenge and a significant burden for the
healthcare system. Skin-resident and infiltrating T cells that recognize pathogens …

In a recent paper published in Science, Konieczny et al. describe that IL-17A produced by
RORγt+ γδ T cells governs wound epithelial cell hypoxic adaptation, which is required for …

Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …

Inflammatory T cells maintain a healing disposition | Science Immunology news careers
commentary Journals Science Science brought to you byGoogle Indexer Log in science science …

Macrophages are the main cells shaping the local microenvironment during wound healing.
As the prime T cells in the skin, γδ T cells participate in regulating microenvironment …