Antibodies play a vital role in the immune response to infectious diseases and can be
administered passively to protect patients. In the case of Cryptococcus neoformans, a WHO …

Cryptococcus neoformans is a fungus classified by the World Health Organization as a
critically important pathogen, which poses a significant threat to immunocompromised …

A convergent synthetic strategy to Cryptococcus neoformans glucuronoxylomannan (GXM)
capsular polysaccharide part structures was developed based on di-, tri-, tetra-, penta-and …

The Cryptococcus neoformans capsular glucuronoxylomannan (GXM) is a potential vaccine
antigen that can elicit protective and non-protective antibodies. In an attempt to focus the …

Galactoxylomannan (GalXM) is a complex polysaccharide produced by the human
pathogenic fungus Cryptococcus neoformans that mediates profound immunological …

The pathogenic encapsulated Cryptococcus neoformans fungus causes serious disease in
immunosuppressed hosts. The capsule, a key virulence factor, consists primarily of the …

Disseminated infections with the fungal species Cryptococcus neoformans or, less
frequently, Cryptococcus gattii are an important cause of mortality in immunocompromised …

Vaccination is a rational alternative to treatment for Cryptococcus neoformans infections, as
these infections are currently intractable in immunocompromised (including HIV-infected) …

Cryptococcus neoformans is a fungal pathogen responsible for cryptococcosis and
cryptococcal meningitis. The C. neoformans' capsular polysaccharide and its shed …

Cryptococcus neoformans causes a life-threatening meningoencephalitis in a significant
percentage of AIDS patients. Mice immunized with a glycoconjugate vaccine composed of …