[HTML][HTML] Exploring drug re-purposing for treatment of abdominal aortic aneurysms: a systematic review and meta-analysis

JSS Kristensen, L Krasniqi, LM Obel… - European Journal of …, 2023 - Elsevier
Objective Large abdominal aortic aneurysms (AAAs) present a significant mortality risk.
While numerous medical interventions have been proposed, no drugs have convincingly …

Pharmacotherapy in clinical trials for abdominal aortic aneurysms: A systematic review and meta-analysis

Z Su, J Guo, Y Gu - Clinical and Applied Thrombosis …, 2022 - journals.sagepub.com
Objective There is no medical treatment proven to limit abdominal aortic aneurysm (AAA)
progression. This systematic review aimed to summarise available trial evidence on the …

[PDF][PDF] The HUNT for a medical treatment of abdominal aortic aneurysms: a systematic review protocol of human studies

JSS Kristensen, E Kavaliunaite, M Liisberg, LM Obel… - crd.york.ac.uk
At this moment, there is no accepted evidence-based implemented medication to halt the
progression of an abdominal aortic aneurysm. Developing a new medical treatment must be …

Research advances in drug therapy for abdominal aortic aneurysms over the past five years: An updated narrative review

R Li, Y Liu, J Jiang - International Journal of Cardiology, 2023 - Elsevier
Background Abdominal aortic aneurysms (AAA) rupture can lead to patient death. Surgical
treatment is currently the optimal treatment for AAA with large diameter (≥ 50 mm). For AAA …

[HTML][HTML] Editor's choice–pharmaceutical management of small abdominal aortic aneurysms: a systematic review of the clinical evidence

VBC Kokje, JF Hamming, JHN Lindeman - European Journal of Vascular …, 2015 - Elsevier
Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

Pharmaceutical management of small abdominal aortic aneurysms: A systematic review of the clinical evidence

VBC Kokje, JF Hamming… - Journal of Vascular …, 2015 - jvascsurg.org
Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

[HTML][HTML] The efficacy of pharmacotherapy for decreasing the expansion rate of abdominal aortic aneurysms: a systematic review and meta-analysis

I Guessous, D Periard, D Lorenzetti, J Cornuz… - PLoS …, 2008 - journals.plos.org
Background Pharmacotherapy may represent a potential means to limit the expansion rate
of abdominal aortic aneurysms (AAAs). Studies evaluating the efficacy of different …

Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

[HTML][HTML] A systematic review and meta-analysis of the incidence and risk factors for major adverse cardiovascular events in patients with unrepaired abdominal aortic …

C Sharma, TP Singh, S Thanigaimani, D Nastasi… - Biomedicines, 2023 - mdpi.com
Major adverse cardiovascular events (MACE), including myocardial infarction (MI), stroke
and cardiovascular death, cause substantial morbidity and mortality. This review assessed …

[HTML][HTML] Challenges and opportunities in limiting abdominal aortic aneurysm growth

J Golledge, PE Norman, MP Murphy… - Journal of vascular …, 2017 - Elsevier
Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …