Approaches to test the neurotoxicity of environmental contaminants in the zebrafish model: From behavior to molecular mechanisms
JA Fitzgerald, S Könemann… - Environmental …, 2021 - Wiley Online Library
The occurrence of neuroactive chemicals in the aquatic environment is on the rise and
poses a potential threat to aquatic biota of currently unpredictable outcome. In particular …
poses a potential threat to aquatic biota of currently unpredictable outcome. In particular …
The utility of zebrafish as a model for screening developmental neurotoxicity
M d'Amora, S Giordani - Frontiers in neuroscience, 2018 - frontiersin.org
The developing central nervous system and the blood brain barrier are especially
vulnerable and sensitive to different chemicals, including environmental contaminants and …
vulnerable and sensitive to different chemicals, including environmental contaminants and …
Comparability of behavioural assays using zebrafish larvae to assess neurotoxicity
J Legradi, N El Abdellaoui, M Van Pomeren… - … Science and Pollution …, 2015 - Springer
Testing of compounds for neurotoxicity has become increasingly important in recent years. It
has been shown that neurological disorders like autism may be related to chemical …
has been shown that neurological disorders like autism may be related to chemical …
Zebrafish as a neurotoxicological model
E Linney, L Upchurch, S Donerly - Neurotoxicology and teratology, 2004 - Elsevier
At a time when common regulatory pathways are being identified in several different species
and genomics is beginning to allow comparisons of genes, how they are arranged on …
and genomics is beginning to allow comparisons of genes, how they are arranged on …
Zebrafish as potential model for developmental neurotoxicity testing: a mini review
The zebrafish is a powerful toxicity model; biochemical assays can be combined with
observations at a structural and functional level within one individual. This mini review …
observations at a structural and functional level within one individual. This mini review …
Rapid zebrafish behavioral profiling assay accelerates the identification of environmental neurodevelopmental toxicants
Rapid and cost-effective in vivo assays to screen potential environmental
neurodevelopmental toxicants are necessary to address the limitations of in vitro platforms …
neurodevelopmental toxicants are necessary to address the limitations of in vitro platforms …
[HTML][HTML] Behavioural assessments of neurotoxic effects and neurodegeneration in zebrafish
KB Tierney - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2011 - Elsevier
Altered neurological function will generally be behaviourally apparent. Many of the
behavioural models pioneered in mammalian models are portable to zebrafish. Tests are …
behavioural models pioneered in mammalian models are portable to zebrafish. Tests are …
Zebrafish get connected: investigating neurotransmission targets and alterations in chemical toxicity
KA Horzmann, JL Freeman - Toxics, 2016 - mdpi.com
Neurotransmission is the basis of neuronal communication and is critical for normal brain
development, behavior, learning, and memory. Exposure to drugs and chemicals can alter …
development, behavior, learning, and memory. Exposure to drugs and chemicals can alter …
Investigating the neurotoxicity of environmental pollutants using zebrafish as a model organism: A review and recommendations for future work
W Lin, Z Huang, W Zhang, Y Ren - Neurotoxicology, 2023 - Elsevier
With the continuous development of precise detection technology, more and more pollutants
have been detected in the environment. Among them, neurotoxic pollutants have attracted …
have been detected in the environment. Among them, neurotoxic pollutants have attracted …
Zebrafish neurotransmitter systems as potential pharmacological and toxicological targets
EP Rico, DB Rosemberg, KJ Seibt, KM Capiotti… - Neurotoxicology and …, 2011 - Elsevier
Recent advances in neurobiology have emphasized the study of brain structure and function
and its association with numerous pathological and toxicological events. Neurotransmitters …
and its association with numerous pathological and toxicological events. Neurotransmitters …