The occurrence of reactive oxygen species, known as pro-oxidants, is an attribute of normal
aerobic life. The steady-state formation of pro-oxidants is balanced by a similar rate of their …

The steady-state formation of prooxidants in cells and organs is balanced by a similar rate of
their consumption by antioxidants that are enzymatic and/or nonenzymatic.“Oxidative stress” …

The role played by free radicals in normal physiology and in human diseases is reviewed.
Oxidative stress occurs in most, if not all, human diseases. Understanding of the role played …

Oxidative stress: concept, implications and modulating factors Page 1 ESTRESSE OXIDATIVO |
629 Rev. Nutr., Campinas, 23(4):629-643, jul./ago., 2010 Revista de Nutrição COMUNICAÇÃO …

Increased free radicals formation derived from abnormal metabolism of oxygen has been
implicated in over 100 different human diseases which may be classified into six categories …

This article reviews aspects of past, present and future potential of oxidants and antioxidants
in clinical medicine. Beginning with the observation that antioxidants help to defend against …

Reactive oxygen species are regarded as merely pernicious. This is incorrect for they play a
pivotal role in many physiologic reactions, such as cytochrome P450-mediated oxidations …

Oxygen-derived free radicals are very important mediators of cell injury and death. Not only
are these highly reactive chemical species important in the aging process, but they are …

Free radicals are reactive chemical species that differ from other compounds in that they
have unpaired electrons in their outer orbitals. They are capable of damaging cellular …

Considerable interest has risen in the idea that oxidative stress is instrumental in the
etiology of numerous human diseases. Oxidative stress can arise through the increased …