Objective Birth asphyxia (BA) is the most frequent cause of neonatal death as well as central
nervous system (CNS) injury. BA is often associated with neonatal seizures, which only …

Birth asphyxia and the resulting hypoxic-ischemic encephalopathy (HIE) are highly
associated with perinatal and neonatal death, neonatal seizures, and an adverse later-life …

Objective Neonatal seizures are the most frequent type of neurological emergency in
newborn infants, often being a consequence of prolonged perinatal asphyxia. Phenobarbital …

Status epilepticus is common in neonates and infants, and is associated with neuronal injury
and adverse developmental outcomes. γ‐Aminobutyric acidergic (GABAergic) drugs, the …

Background: There is controversy over whether seizures, the most common manifestation of
neonatal brain injury, may themselves damage the developing brain. Objective: To …

In the pediatric age group, the risk of seizures is highest in the neonatal period. 1 However,
neonatal seizures are often refractory to conventional anticonvulsant drug therapy. An …

Kaila, Löscher, and colleagues report that phenobarbital (PHB) and midazolam (MDZ)
attenuate neonatal seizures following birth asphyxia, but the former only when applied …

Identifying which specific neuronal phenotypes are vulnerable to neonatal hypoxia‐
ischemia, where in the brain they are damaged, and the mechanisms that produce neuronal …

Objective Birth asphyxia is a major cause of hypoxic–ischemic encephalopathy (HIE) in
neonates and often associated with mortality, neonatal seizures, brain damage, and later life …

Seizures occurring in infants with hypoxia are frequently associated with an ominous
prognosis. There is, however, no direct evidence that seizures are involved in the …