[HTML][HTML] Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of …

KB Beshir, J Muwanguzi, J Nader… - The Lancet Infectious …, 2023 - thelancet.com
Background Seasonal malaria chemoprevention is used in 13 countries in the Sahel region
of Africa to prevent malaria in children younger than 5 years. Resistance of Plasmodium …

[HTML][HTML] Effect of three years' seasonal malaria chemoprevention on molecular markers of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine and …

A Mahamar, KM Sumner, B Levitt, B Freedman… - Malaria journal, 2022 - Springer
Background In 2012, seasonal malaria chemoprevention (SMC) was recommended as
policy for malaria control by the World Health Organization (WHO) in areas of highly …

[HTML][HTML] Contrasting Asymptomatic and Drug Resistance Gene Prevalence of Plasmodium falciparum in Ghana: Implications on Seasonal Malaria Chemoprevention

CC Dieng, L Gonzalez, K Pestana, SB Dhikrullahi… - Genes, 2019 - mdpi.com
Malaria is a significant public health problem in Ghana. Seasonal Malaria Chemoprevention
(SMC) using a combination of sulfadoxine-pyrimethamine and amodiaquine has been …

[HTML][HTML] Decreased prevalence of Plasmodium falciparum resistance markers to amodiaquine despite its wide scale use as ACT partner drug in Zanzibar

G Fröberg, L Jörnhagen, U Morris, D Shakely… - Malaria journal, 2012 - Springer
Background Zanzibar has recently undergone a rapid decline in Plasmodium falciparum
transmission following combined malaria control interventions with artemisinin-based …

Persistence of sulfadoxine-pyrimethamine resistance despite reduction of drug pressure in Malawi

E Artimovich, K Schneider, TE Taylor… - The Journal of …, 2015 - academic.oup.com
Abstract Background. In 2007, Malawi replaced sulfadoxine-pyrimethamine (SP) with an
artemisinin-based combination therapy as the first-line treatment for uncomplicated …

[HTML][HTML] Drug-resistant polymorphisms and copy numbers in Plasmodium falciparum, Mozambique, 2015

H Gupta, E Macete, H Bulo, C Salvador… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
One of the fundamental steps toward malaria control is the use of antimalarial drugs. The
success of antimalarial treatment can be affected by the presence of drug-resistant …

Molecular surveillance of Plasmodium falciparum drug resistance markers reveals partial recovery of chloroquine susceptibility but sustained sulfadoxine …

F Kateera, SL Nsobya, S Tukwasibwe, E Hakizimana… - Acta tropica, 2016 - Elsevier
Faced with intense levels of chloroquine (CQ) resistance in Plasmodium falciparum malaria,
Rwanda replaced CQ with amodiaquine (AQ)+ sulfadoxine-pyrimethamine (SP) in 2001 …

[HTML][HTML] Genetic diversity of Plasmodium falciparum and distribution of drug resistance haplotypes in Yemen

S Al-Hamidhi, MAK Mahdy, Z Al-Hashami, H Al-Farsi… - Malaria Journal, 2013 - Springer
Background Despite evident success of malaria control in many sites in the Arabian
Peninsula, malaria remains endemic in a few spots, in Yemen and south-west of Saudi …

Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection

DC Nwakanma, CW Duffy… - The Journal of …, 2014 - academic.oup.com
Background. Analysis of genome-wide polymorphism in many organisms has potential to
identify genes under recent selection. However, data on historical allele frequency changes …

[HTML][HTML] Impact of piperaquine resistance in Plasmodium falciparum on malaria treatment effectiveness in The Guianas: a descriptive epidemiological study

C Florimond, F de Laval, AM Early… - The Lancet Infectious …, 2024 - thelancet.com
Background Plasmodium falciparum is an apicomplexan parasite responsible for lethal
cases of malaria. According to WHO recommendations, P falciparum cases are treated with …