[HTML][HTML] Adventitial adipogenic degeneration is an unidentified contributor to aortic wall weakening in the abdominal aortic aneurysm

SA Doderer, G Gäbel, VBC Kokje, BH Northoff… - Journal of Vascular …, 2018 - Elsevier
Objective The processes driving human abdominal aortic aneurysm (AAA) progression are
not fully understood. Although antiinflammatory and proteolytic strategies effectively quench …

Pathological implication of adipocytes in AAA development and the rupture

H Kugo, H Tanaka, T Moriyama… - Annals of Vascular …, 2018 - jstage.jst.go.jp
Abdominal aortic aneurysm (AAA) is a vascular disease that involves the gradual dilation of
the abdominal aorta followed by its rupture. AAA is closely associated with weakening of the …

[HTML][HTML] Heterogeneous histomorphology, yet homogeneous vascular smooth muscle cell dedifferentiation, characterize human aneurysm disease

A Busch, E Hartmann, C Grimm, S Ergün… - Journal of vascular …, 2017 - Elsevier
Objective Abdominal aortic aneurysm (AAA) is a frequent, potentially life-threatening,
disease that can only be treated by surgical means such as open surgery or endovascular …

The role of perivascular adipose tissue in the appearance of ectopic adipocytes in the abdominal aortic aneurysmal wall

H Kugo, T Moriyama, N Zaima - Adipocyte, 2019 - Taylor & Francis
Abdominal aortic aneurysm (AAA) is a vascular disease characterized by the dilation of the
abdominal aorta, resulting in a high mortality rate caused by vascular rupture. Previous …

[HTML][HTML] Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms

M Folkesson, E Vorkapic, E Gulbins, L Japtok… - Journal of Vascular …, 2017 - Elsevier
Background Abdominal aortic aneurysm (AAA) is a deadly irreversible weakening and
distension of the abdominal aortic wall. The pathogenesis of AAA remains poorly …

Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm

H Kugo, N Zaima, H Tanaka, Y Mouri, K Yanagimoto… - Scientific reports, 2016 - nature.com
Abdominal aortic aneurysm (AAA) is a vascular disease involving the gradual dilation of the
abdominal aorta. It has been reported that development of AAA is associated with …

The pathophysiologic basis of abdominal aortic aneurysm progression: a critical appraisal

JHN Lindeman - Expert review of cardiovascular therapy, 2015 - Taylor & Francis
An aneurysm of the abdominal aorta is a common pathology and a major cause of sudden
death in the elderly. Currently, abdominal aortic aneurysms (AAAs) can only be treated by …

[HTML][HTML] Inflammatory gene expression of human perivascular adipose tissue in abdominal aortic aneurysms

JP Meekel, M Dias-Neto, N Bogunovic… - European Journal of …, 2021 - Elsevier
Objective Perivascular adipose tissue (PVAT) contributes to vascular homeostasis and is
increasingly linked to vascular pathology. PVAT density and volume were associated with …

[HTML][HTML] The pathophysiology of abdominal aortic aneurysm growth: corresponding and discordant inflammatory and proteolytic processes in abdominal aortic and …

H Abdul-Hussien, R Hanemaaijer, R Kleemann… - Journal of Vascular …, 2010 - Elsevier
OBJECTIVE: There is remarkable controversy over the processes driving abdominal
aneurysm growth. The inherent limitations of animal and human studies hamper elucidation …

Clinical significance of increased computed tomography attenuation of periaortic adipose tissue in patients with abdominal aortic aneurysms

M Yamaguchi, T Yonetsu, M Hoshino… - Circulation …, 2021 - jstage.jst.go.jp
Background: Recent imaging studies reported an association between vascular
inflammation and progression of abdominal aortic aneurysm (AAA). This study investigated …