The bioartificial pancreas (BAP) represents a viable solution for the treatment of type 1
diabetes (T1D). By encapsulating pancreatic cells in a semipermeable membrane to allow …

This paper presents the concept and most of the research undertaken all over the world for
the development of a bio‐artificial pancreas (BAP) device over the last 30 years. The …

The term" bioartificial endocrine pancreas"(BEP) was introduced by Anthony Sun in 1980. It
was in 1968, however, that Thomas Chang proposed the use of microencapsulated islets as …

Recent advances in islet transplantation using highly purified islets and effective
immunosuppression strategies have resulted in substantial improvement in achieving …

Substitution of diseased organ/tissues with totally artificial machines or transplantable
biohybrid devices where functionally competent cells are enveloped within …

Pancreatic islet transplantation has been validated as a treatment for type 1 diabetes since it
maintains consistent and sustained type 1 diabetes reversal. However, one of the major …

Type 1 diabetes mellitus is a common and highly morbid disease for which there is no cure.
Treatment primarily involves exogenous insulin administration, and, under specific …

Diabetes remains a devastating disease, with tremendous cost in terms of human suffering
and healthcare expenditures. A bioartificial pancreas has the potential as a promising …

The current interest for the development of a bioartificial pancreas is impressive. At least 10
groups working in this field are identified. Over the last 2 years, several papers have been …

The pancreas is a dual-function organ featuring both endocrine and exocrine tissue.
Endocrine functionality is provided by approximately one million cell clusters called the islets …