Mechanisms of Pulmonary Escape and Dissemination by Cryptococcus neoformans
Cryptococcus neoformans is a common environmental saprophyte and human fungal
pathogen that primarily causes disease in immunocompromised individuals. Similar to many …
pathogen that primarily causes disease in immunocompromised individuals. Similar to many …
Cryptococcus–Epithelial Interactions
LM Taylor-Smith - Journal of Fungi, 2017 - mdpi.com
The fungal pathogen, Cryptococcus neoformans, causes devastating levels of morbidity and
mortality. Infections with this fungus tend to be predominantly in immunocompromised …
mortality. Infections with this fungus tend to be predominantly in immunocompromised …
Dueling in the lung: how Cryptococcus spores race the host for survival
MR Botts, CM Hull - Current opinion in microbiology, 2010 - Elsevier
Many human fungal pathogens infect people when they are inhaled as spores. Despite the
serious impact of fungal spores on human health, little is known about their basic properties …
serious impact of fungal spores on human health, little is known about their basic properties …
Paradoxical roles of alveolar macrophages in the host response to Cryptococcus neoformans
TJ McQuiston, PR Williamson - Journal of Infection and Chemotherapy, 2012 - Elsevier
Cryptococcus neoformans (Cn) is a fungal pathogen that is a serious health threat to
immunocompromised individuals. Upon environmental exposure, infectious fungal …
immunocompromised individuals. Upon environmental exposure, infectious fungal …
Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans
BN Nelson, AN Hawkins, KL Wozniak - Frontiers in cellular and …, 2020 - frontiersin.org
The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in
immune compromised individuals. This pathogen is typically acquired via inhalation, and …
immune compromised individuals. This pathogen is typically acquired via inhalation, and …
A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans
Environmental pathogens move from ecological niches to mammalian hosts, requiring
adaptation to dramatically different environments. Microbes that disseminate farther …
adaptation to dramatically different environments. Microbes that disseminate farther …
New insights on the pathogenesis of invasive Cryptococcus neoformans infection
HC Eisenman, A Casadevall, EE McClelland - Current Infectious Disease …, 2007 - Springer
Disseminated cryptococcosis begins with infection of the lungs via inhalation. This is
followed by escape from the lungs and entry into the bloodstream allowing dissemination to …
followed by escape from the lungs and entry into the bloodstream allowing dissemination to …
Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host
MS Price, M Betancourt-Quiroz, JL Price, DL Toffaletti… - MBio, 2011 - Am Soc Microbiol
Cryptococcus neoformans is an important fungal pathogen of immunocompromised
individuals, with a close relative, Cryptococcus gattii, emerging as a serious threat for the …
individuals, with a close relative, Cryptococcus gattii, emerging as a serious threat for the …
The tools for virulence of Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …
each year. It is believed that most humans are infected with C. neoformans, possibly in a …
Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box
JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …
because of its tendency to infect immunocompromised individuals, particularly those …