Antigen presentation lies at the heart of immune recognition of infected or malignant cells.
For this reason, important efforts have been made to predict which peptides are more likely …

Increasing evidence indicates CD4+ T cells can recognize cancer-specific antigens and
control tumor growth. However, it remains difficult to predict the antigens that will be …

The precise identification of Human Leukocyte Antigen class I (HLA-I) binding motifs plays a
central role in our ability to understand and predict (neo-) antigen presentation in infectious …

The presentation of peptides on class I human leukocyte antigen (HLA-I) molecules plays a
central role in immune recognition of infected or malignant cells. In cancer, non-self HLA-I …

Prediction of HLA epitopes is important for the development of cancer immunotherapies and
vaccines. However, current prediction algorithms have limited predictive power, in part …

A challenge in developing personalized cancer immunotherapies is the prediction of
putative cancer‐specific antigens. Currently, predictive algorithms are used to infer binding …

Human leukocyte antigens (HLA) are cell-surface proteins that present peptides to T cells.
These peptides are bound within the peptide binding cleft of HLA, and together as a …

Identification of human leukocyte antigen (HLA)-bound peptides by liquid chromatography-
tandem mass spectrometry (LC-MS/MS) is poised to provide a deep understanding of rules …

The entirety of human leukocyte antigen (HLA)‐presented peptides is referred to as the HLA
ligandome of a cell or tissue, in tumours often termed immunopeptidome. Mapping the …

The classical HLA-C and the nonclassical HLA-E and HLA-G molecules play important roles
both in the innate and adaptive immune system. Starting already during embryogenesis and …