Assessing the association between homocysteine and cognition: reflections on Bradford Hill, meta-analyses, and causality
A McCaddon, JW Miller - Nutrition reviews, 2015 - academic.oup.com
Hyperhomocysteinemia is a recognized risk factor for cognitive decline and incident
dementia in older adults. Two recent reports addressed the cumulative epidemiological …
dementia in older adults. Two recent reports addressed the cumulative epidemiological …
Effect of homocysteine lowering treatment on cognitive function: a systematic review and meta-analysis of randomized controlled trials
AH Ford, OP Almeida - Journal of Alzheimer's Disease, 2012 - content.iospress.com
Elevated total plasma homocysteine has been linked to the development of cognitive
impairment and dementia in later life and this can be reliably lowered by the daily …
impairment and dementia in later life and this can be reliably lowered by the daily …
B-vitamins and prevention of dementia: Plenary Lecture
R Clarke - Proceedings of the Nutrition Society, 2008 - cambridge.org
Elevated plasma homocysteine (Hcy) concentrations have been implicated with risk of
cognitive impairment and dementia, but it is unclear whether low vitamin B12 or folate status …
cognitive impairment and dementia, but it is unclear whether low vitamin B12 or folate status …
[HTML][HTML] Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals
R Clarke, D Bennett, S Parish, S Lewington… - The American journal of …, 2014 - Elsevier
Background: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the
relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain …
relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain …
Homocysteine, B vitamins, and cognitive impairment
AD Smith, H Refsum - Annual review of nutrition, 2016 - annualreviews.org
Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …
A critical evaluation of the relationship between serum vitamin B12, folate and total homocysteine with cognitive impairment in the elderly
M Ellinson, J Thomas… - Journal of Human Nutrition …, 2004 - Wiley Online Library
Background Serum homocysteine increases with age and is also considered a marker for
low serum vitamin B12 and folate. Furthermore, raised serum total homocysteine has been …
low serum vitamin B12 and folate. Furthermore, raised serum total homocysteine has been …
[HTML][HTML] Homocysteine and mild cognitive impairment: Are these the tools for early intervention in the dementia spectrum?
Z Ansari - The Journal of nutrition, health and aging, 2016 - Elsevier
Dementia, being a neurodegenerative disease, has devastating consequences not just for
the ailing but also for the carers as it has a tremendous negative impact on the quality of life …
the ailing but also for the carers as it has a tremendous negative impact on the quality of life …
Homocysteine: A modifiable culprit of cognitive impairment for us to conquer?
Y Ji, P Lyu, W Jin, X Li, X Li, Y Dong - Journal of the Neurological Sciences, 2019 - Elsevier
Background Cognitive impairment, including mild cognitive impairment and its progressive
deterioration to dementia, results in great hazards to the patient and the surrounding society …
deterioration to dementia, results in great hazards to the patient and the surrounding society …
Effect of vitamin B supplementation on cognitive function in the elderly: a systematic review and meta-analysis
AH Ford, OP Almeida - Drugs & aging, 2019 - Springer
Background Vitamin B deficiency and elevated total plasma homocysteine have been
associated with cognitive impairment and dementia in later life, although it is unknown if …
associated with cognitive impairment and dementia in later life, although it is unknown if …
Hyperhomocysteinemia and risk of incident cognitive outcomes: an updated dose-response meta-analysis of prospective cohort studies
F Zhou, S Chen - Ageing research reviews, 2019 - Elsevier
Objective This study aimed to comprehensively assess the dose-response relationship
between blood homocysteine levels and risk of all cause, Alzheimer and vascular dementia …
between blood homocysteine levels and risk of all cause, Alzheimer and vascular dementia …