Objectives Currently there is no drug therapy for abdominal aortic aneurysm (AAA) and most
previous investigations have focused on imaging rather than clinical outcomes. The aim of …

Objective A meta-analysis of the association between metformin prescription and abdominal
aortic aneurysm (AAA) growth and events (rupture or surgical repair) was performed …

Background Multiple observational studies have associated metformin prescription with
reduced progression of abdominal aortic aneurysm (AAA). The Metformin Aneurysm Trial …

Objective Diabetes counteracts formation and rupture of abdominal aortic aneurysms,
possibly through arterial matrix accumulation. Use of metformin, on the other hand, reduces …

Recently published data from a number of sources appear to suggest that the oral
hypoglycaemic agent metformin may prevent abdominal aortic aneurysm (AAA) …

Background It has been suggested that diabetes medications, such as metformin, may have
effects that inhibit abdominal aortic aneurysm (AAA) growth. The aim of this study was to …

Background Identification of a safe and effective medical therapy for abdominal aortic
aneurysm (AAA) disease remains a significant unmet medical need. Recent small cohort …

Worldwide about 20 million people have an abdominal aortic aneurysm (AAA) and rupture
leads to approximately 200 000 deaths annually. To prevent rupture, early detection and …

We sought to examine the progression from abdominal aortic aneurysm (AAA) diagnosis to
surgery and death among diabetics with and without exposure to metformin as well as non …

Objective In population-based studies performed on multiple continents during the past two
decades, diabetes mellitus has been negatively associated with the prevalence and …