Consistent gene signature of schizophrenia identified by a novel feature selection strategy from comprehensive sets of transcriptomic data
The etiology of schizophrenia (SCZ) is regarded as one of the most fundamental puzzles in
current medical research, and its diagnosis is limited by the lack of objective molecular …
current medical research, and its diagnosis is limited by the lack of objective molecular …
Schizophrenia gene networks and pathways and their applications for novel candidate gene selection
Background Schizophrenia (SZ) is a heritable, complex mental disorder. We have seen
limited success in finding causal genes for schizophrenia from numerous conventional …
limited success in finding causal genes for schizophrenia from numerous conventional …
Identifying crucial biomarkers in peripheral blood of schizophrenia and screening therapeutic agents by comprehensive bioinformatics analysis
M Xie, Z Li, X Li, L Ai, M Jin, N Jia, Y Yang, W Li… - Journal of psychiatric …, 2022 - Elsevier
Schizophrenia (SCZ) is a sophisticated neurodevelopmental disorder, but the mechanisms
remain ambiguous. Thus, we analyzed the transcriptomic datasets to investigate the …
remain ambiguous. Thus, we analyzed the transcriptomic datasets to investigate the …
Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction
F Guan, T Ni, W Zhu, LK Williams, LB Cui, M Li… - Molecular …, 2022 - nature.com
Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …
complex inheritance. In the past decade, successful identification of numerous susceptibility …
SZGR: a comprehensive schizophrenia gene resource
Schizophrenia is a major debilitating psychiatric disorder affecting∼ 1% of the population
worldwide. A tremendous amount of effort has been expended in the last two decades to …
worldwide. A tremendous amount of effort has been expended in the last two decades to …
A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases–schizophrenia as a case
Motivation: During the past decade, we have seen an exponential growth of vast amounts of
genetic data generated for complex disease studies. Currently, across a variety of complex …
genetic data generated for complex disease studies. Currently, across a variety of complex …
SZDB: a database for schizophrenia genetic research
Y Wu, YG Yao, XJ Luo - Schizophrenia bulletin, 2017 - academic.oup.com
Schizophrenia (SZ) is a debilitating brain disorder with a complex genetic architecture.
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …
Identification of potential biomarkers and their correlation with immune infiltration cells in schizophrenia using combinative bioinformatics strategy
Z Li, X Li, M Jin, Y Liu, Y He, N Jia, X Cui, Y Liu, G Hu… - Psychiatry …, 2022 - Elsevier
Many studies have identified changes in gene expression in brains of schizophrenia
patients and their altered molecular processes, but the findings in different datasets were …
patients and their altered molecular processes, but the findings in different datasets were …
Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data
Unlike the typical analysis of single markers in genome-wide association studies (GWAS),
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results
AL Collins, Y Kim, P Sklar, MC O'Donovan… - Psychological …, 2012 - cambridge.org
BackgroundCandidate gene studies have been a key approach to the genetics of
schizophrenia (SCZ). However, the results of these studies are confusing and no genes …
schizophrenia (SCZ). However, the results of these studies are confusing and no genes …