Vascular smooth muscle cells phenotypic switching in cardiovascular diseases
HY Tang, AQ Chen, H Zhang, XF Gao, XQ Kong… - Cells, 2022 - mdpi.com
Vascular smooth muscle cells (VSMCs), the major cell type in the arterial vessel wall, have a
contractile phenotype that maintains the normal vessel structure and function under …
contractile phenotype that maintains the normal vessel structure and function under …
An update on the phenotypic switching of vascular smooth muscle cells in the pathogenesis of atherosclerosis
F Zhang, X Guo, Y Xia, L Mao - Cellular and Molecular Life Sciences, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are involved in phenotypic switching in
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …
[HTML][HTML] Targeting smooth muscle cell phenotypic switching in vascular disease
Objective The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to
vessel growth and remodeling, but also contributes to cardiovascular pathologies. New …
vessel growth and remodeling, but also contributes to cardiovascular pathologies. New …
How vascular smooth muscle cell phenotype switching contributes to vascular disease
G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
Role of vascular smooth muscle cell phenotype switching in arteriogenesis
JV Ashraf, A Al Haj Zen - International journal of molecular sciences, 2021 - mdpi.com
Arteriogenesis is one of the primary physiological means by which the circulatory collateral
system restores blood flow after significant arterial occlusion in peripheral arterial disease …
system restores blood flow after significant arterial occlusion in peripheral arterial disease …
[HTML][HTML] Role of smooth muscle cells in Cardiovascular Disease
Y Zhuge, J Zhang, F Qian, Z Wen, C Niu… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Normally, smooth muscle cells (SMCs) are localized in the tunica media of the vasculature,
where they take responsibility for vascular contraction and extracellular matrix (ECM) …
where they take responsibility for vascular contraction and extracellular matrix (ECM) …
Fate and state of vascular smooth muscle cells in atherosclerosis
Vascular smooth muscle cells (VSMCs) have long been associated with phenotypic
modulation/plasticity or dedifferentiation. Innovative technologies in cell lineage tracing …
modulation/plasticity or dedifferentiation. Innovative technologies in cell lineage tracing …
Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity
A Frismantiene, M Philippova, P Erne, TJ Resink - Cellular signalling, 2018 - Elsevier
Vascular smooth muscle cells (VSMCs) are the major cell type in blood vessels. Unlike
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and …
Background: Smooth muscle cells (SMCs) play significant roles in atherosclerosis via
phenotypic switching, a pathological process in which SMC dedifferentiation, migration, and …
phenotypic switching, a pathological process in which SMC dedifferentiation, migration, and …
Smooth muscle cells in vascular remodeling
As the primary causes of myocardial infarction, stroke, atherosclerosis, in-stent restenosis,
and aneurysm, aortic diseases pose a serious threat to human health. Arterial remodeling is …
and aneurysm, aortic diseases pose a serious threat to human health. Arterial remodeling is …
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