Hepatocellular carcinoma mechanisms associated with chronic HCV infection and the impact of direct-acting antiviral treatment

S Dash, Y Aydin, KE Widmer… - Journal of hepatocellular …, 2020 - Taylor & Francis
Hepatitis C virus (HCV) infection is the major risk factor for liver cirrhosis and hepatocellular
carcinoma (HCC). The mechanisms of HCC initiation, growth, and metastasis appear to be …

Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma

S Bandiera, CB Bian, Y Hoshida, TF Baumert… - Current opinion in …, 2016 - Elsevier
Highlights•The molecular mechanisms of HCV-driven HCC are still elusive.•HCV perturbs
hepatocellular homeostasis by driving several major cancer hallmarks.•HCV-induced …

Pathogenesis of hepatitis C—associated hepatocellular carcinoma

TJ Liang, T Heller - Gastroenterology, 2004 - Elsevier
Epidemiologic, clinical, and virologic data have shown a close association between chronic
infection with hepatitis C virus (HCV) and the development of hepatocellular carcinoma …

[HTML][HTML] Hepatocellular carcinoma in chronic viral hepatitis: where do we stand?

FP Russo, A Zanetto, E Pinto, S Battistella… - International journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death.
Although the burden of alcohol-and NASH-related HCC is growing, chronic viral hepatitis …

[HTML][HTML] Hepatitis C virus and hepatocellular carcinoma: when the host loses its grip

K Goto, AA Roca Suarez, F Wrensch… - International journal of …, 2020 - mdpi.com
Chronic infection with hepatitis C virus (HCV) is a major cause of hepatocellular carcinoma
(HCC). Novel treatments with direct-acting antivirals achieve high rates of sustained …

HCV eradication induced by direct-acting antiviral agents reduces the risk of hepatocellular carcinoma

GN Ioannou, PK Green, K Berry - Journal of hepatology, 2018 - Elsevier
Background & Aims It is unclear whether direct-acting antiviral (DAA) treatment-induced
sustained virologic response (SVR) reduces the risk of hepatocellular carcinoma (HCC) in …

Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer

DR McGivern, SM Lemon - Oncogene, 2011 - nature.com
The development of hepatocellular carcinoma (HCC) in persons who are persistently
infected with hepatitis C virus (HCV) is a growing problem worldwide. Current antiviral …

[HTML][HTML] Hepatocellular carcinoma in patients with chronic hepatitis C virus infection in the Asia–Pacific region

MN Kim, BK Kim, KH Han - Journal of gastroenterology, 2013 - Springer
Hepatocellular carcinoma (HCC) is the third-leading cause of cancer-related mortality
worldwide. Although hepatitis B still remains the most common risk factor worldwide, chronic …

[HTML][HTML] Hepatitis C virus and hepatocellular carcinoma: a narrative review

P Axley, Z Ahmed, S Ravi, AK Singal - Journal of clinical and …, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a leading cause of liver-related death worldwide.
Hepatitis C virus (HCV) infection is a major cause of advanced hepatic fibrosis and cirrhosis …

[HTML][HTML] Hepatocellular carcinoma in patients with a sustained response to anti-hepatitis C therapy

R D'Ambrosio, C Della Corte, M Colombo - International journal of …, 2015 - mdpi.com
Hepatocellular carcinoma (HCC) is a common, life-threatening complication of longstanding
infection with the hepatitis C virus (HCV), likely a consequence of the direct oncogenic …