[PDF][PDF] Extracellular vesicle mitochondrial DNA levels are associated with race and mitochondrial DNA haplogroup
Circulating cell-free mitochondrial DNA (ccf-mtDNA) acts as a damage-associated molecular
pattern molecule and may be cargo within extracellular vesicles (EVs). ccf-mtDNA and select …
pattern molecule and may be cargo within extracellular vesicles (EVs). ccf-mtDNA and select …
Association Between Whole Blood–Derived Mitochondrial DNA Copy Number, Low‐Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk
Background The relationship between mitochondrial DNA copy number (mtDNA CN) and
cardiovascular disease remains elusive. Methods and Results We performed cross …
cardiovascular disease remains elusive. Methods and Results We performed cross …
[PDF][PDF] Association of mitochondrial DNA copy number with cardiometabolic diseases
Mitochondrial DNA (mtDNA) is present in multiple copies in human cells. We evaluated
cross-sectional associations of whole-blood mtDNA copy number (CN) with several …
cross-sectional associations of whole-blood mtDNA copy number (CN) with several …
Exploring mitochondrial DNA copy number in circulating cell‐free DNA and extracellular vesicles across cardiovascular health status: A prospective case–control pilot …
C Rucci, G de Simone, S Salathia… - The FASEB …, 2024 - Wiley Online Library
Cardiovascular disease (CVD) is a leading global cause of mortality, difficult to predict in
advance. Evidence indicates that the copy number of mitochondrial DNA (mtDNAcn) in …
advance. Evidence indicates that the copy number of mitochondrial DNA (mtDNAcn) in …
Blood-derived mitochondrial DNA copy number is associated with gene expression across multiple tissues and is predictive for incident neurodegenerative disease
Mitochondrial DNA copy number (mtDNA-CN) is a proxy for mitochondrial function and is
associated with aging-related diseases. However, it is unclear how mtDNA-CN measured in …
associated with aging-related diseases. However, it is unclear how mtDNA-CN measured in …
Association of mitochondrial DNA copy number with cardiovascular disease
Importance Mitochondrial dysfunction is a core component of the aging process and may
play a key role in atherosclerotic cardiovascular disease. Mitochondrial DNA copy number …
play a key role in atherosclerotic cardiovascular disease. Mitochondrial DNA copy number …
Mitochondrial DNA content is linked to cardiovascular disease patient phenotypes
R Wei, Y Ni, P Bazeley, S Grandhi, J Wang… - Journal of the …, 2021 - Am Heart Assoc
Background We sought to determine whether mitochondrial DNA (mtDNA) content can be
used as markers for 12 key phenotypes among cardiovascular disease patients, and …
used as markers for 12 key phenotypes among cardiovascular disease patients, and …
Association of mitochondrial DNA levels with frailty and all-cause mortality
Mitochondrial function is altered with age and variants in mitochondrial DNA (mtDNA)
modulate risk for several age-related disease states. However, the association of mtDNA …
modulate risk for several age-related disease states. However, the association of mtDNA …
[HTML][HTML] Heteroplasmic mitochondrial DNA variants in cardiovascular diseases
Mitochondria are implicated in the pathogenesis of cardiovascular diseases (CVDs) but the
reasons for this are not well understood. Maternally-inherited population variants of …
reasons for this are not well understood. Maternally-inherited population variants of …
Association of mitochondrial DNA copy number with cardiometabolic diseases in a large cross-sectional study of multiple ancestries
The mitochondrial genome (mtDNA) is represented at variable copy number (CN) in human
cells and plays essential roles in cellular metabolism. Previous studies reported inconsistent …
cells and plays essential roles in cellular metabolism. Previous studies reported inconsistent …