Exposure to ultrafine particulate matter induces NF-κβ mediated epigenetic modifications

A Bhargava, A Shukla, N Bunkar, R Shandilya… - Environmental …, 2019 - Elsevier
Exposure to ultrafine particulate matter (PM0. 1) is positively associated with the etiology of
different acute and chronic disorders; however, the in-depth biological imprints that link …

Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes

A Bhargava, S Tamrakar, A Aglawe, H Lad… - Environmental …, 2018 - Elsevier
Particulate matter (PM), broadly defined as coarse (2.5–10 μm), fine (0.1–2.5 μm) and
ultrafine particles (≤ 0.1 μm), is a major constituent of ambient air pollution. Recent studies …

Inhaled pollutants: the molecular scene behind respiratory and systemic diseases associated with ultrafine particulate matter

H Traboulsi, N Guerrina, M Iu, D Maysinger… - International journal of …, 2017 - mdpi.com
Air pollution of anthropogenic origin is largely from the combustion of biomass (eg, wood),
fossil fuels (eg, cars and trucks), incinerators, landfills, agricultural activities and tobacco …

Comparison of gene expression profiles induced by coarse, fine, and ultrafine particulate matter

YCT Huang, ED Karoly, LA Dailey… - Journal of Toxicology …, 2011 - Taylor & Francis
Coarse, fine, and ultrafine particulate matter (PM) fractions possess different physical
properties and chemical compositions and may produce different adverse health effects …

Gene expression profile in circulating mononuclear cells after exposure to ultrafine carbon particles

YCT Huang, M Schmitt, Z Yang, LG Que… - Inhalation …, 2010 - Taylor & Francis
Context: Exposure to particulate matter (PM) is associated with systemic health effects, but
the cellular and molecular mechanisms are unclear. Objective: We hypothesized that, if …

Particulate matter toxicity is Nrf2 and mitochondria dependent: the roles of metals and polycyclic aromatic hydrocarbons

M Pardo, X Qiu, R Zimmermann… - Chemical research in …, 2020 - ACS Publications
Particulate matter (PM), an important component of air pollution, induces significant adverse
health effects. Many of the observed health effects caused by inhaled PM are associated …

Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways

MT Kleinman, JA Araujo, A Nel, C Sioutas, A Campbell… - Toxicology letters, 2008 - Elsevier
In addition to evidence that inhalation of ambient particulate matter (PM) can increase
cardiopulmonary morbidity and mortality, the brain may also constitute a site adversely …

Multi-omics analysis to reveal disorders of cell metabolism and integrin signaling pathways induced by PM2. 5

X Song, J Liu, N Geng, Y Shan, B Zhang, B Zhao… - Journal of Hazardous …, 2022 - Elsevier
Atmospheric fine particle pollution is known to cause many adverse health effects. However,
the potential mechanisms of PM 2.5-induced cytotoxicity still needs further understanding …

Integrated mitoepigenetic signalling mechanisms associated with airborne particulate matter exposure: A cross-sectional pilot study

PK Mishra, A Bhargava, R Kumari, N Bunkar… - Atmospheric Pollution …, 2022 - Elsevier
Airborne particulate matter (PM) is known to be associated with various chronic human
ailments, however, precise underlying molecular mechanisms remains elusive. Based on …

Transcriptional profiling of human bronchial epithelial cell BEAS-2B exposed to diesel and biomass ultrafine particles

A Grilli, R Bengalli, E Longhin, L Capasso… - Bmc Genomics, 2018 - Springer
Background Emissions from diesel vehicles and biomass burning are the principal sources
of primary ultrafine particles (UFP). The exposure to UFP has been associated to …