[HTML][HTML] Inflammasomes in the pathophysiology of aortic disease
M Wortmann, AS Peters, P Erhart, D Körfer, D Böckler… - Cells, 2021 - mdpi.com
Aortic diseases comprise aneurysms, dissections, and several other pathologies. In general,
aging is associated with a slow but progressive dilation of the aorta, along with increased …
aging is associated with a slow but progressive dilation of the aorta, along with increased …
[HTML][HTML] Inflammasome activity in leucocytes decreases with abdominal aortic aneurysm progression
P Erhart, S Cakmak… - International …, 2019 - spandidos-publications.com
Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammatory cell
infiltration. The present extended immunohistochemistry study aimed to characterize …
infiltration. The present extended immunohistochemistry study aimed to characterize …
[HTML][HTML] Inflammasomes in Atherosclerosis—From Pathophysiology to Treatment
Atherosclerosis, a chronic inflammatory disease characterized by arterial plaque
accumulation, remains a significant global health challenge. In recent years …
accumulation, remains a significant global health challenge. In recent years …
Aortic wall inflammation in the pathogenesis, diagnosis and treatment of aortic aneurysms
G Skotsimara, A Antonopoulos, E Oikonomou… - Inflammation, 2022 - Springer
The role of inflammation in the development of aortic aneurysms is emerging, along with the
potential diagnostic and therapeutical potential of this correlation. Abdominal aorta …
potential diagnostic and therapeutical potential of this correlation. Abdominal aorta …
[HTML][HTML] Increased expression and activation of absent in melanoma 2 inflammasome components in lymphocytic infiltrates of abdominal aortic aneurysms
S Dihlmann, P Erhart, A Mehrabi, A Nickkholgh… - Molecular …, 2014 - Springer
Chronic vascular inflammation is a key hallmark in the pathogenesis of abdominal aortic
aneurysm (AAA). Recent investigations have suggested that the inflammasome, a cytosolic …
aneurysm (AAA). Recent investigations have suggested that the inflammasome, a cytosolic …
The inflammasomes in cardiovascular disease
GPJ van Hout, L Bosch - Inflammasomes: Clinical and Therapeutic …, 2018 - Springer
Cardiovascular disease (CVD) is the number one cause of death worldwide. The
pathogenesis of various disease entities that comprise the area of CVD is complex and …
pathogenesis of various disease entities that comprise the area of CVD is complex and …
The role of the inflammasome in cardiovascular diseases
X Li, N Deroide, Z Mallat - Journal of molecular medicine, 2014 - Springer
Inflammasome is a very important signaling platform sensing a variety of triggers of the
innate immune system. Inflammasome promotes the production of important pro …
innate immune system. Inflammasome promotes the production of important pro …
Inflammasomes in the pathophysiology of kidney diseases
H Masood, R Che, A Zhang - Kidney Diseases, 2015 - karger.com
Background: The inflammasome is a complex of proteins in the cytoplasm that consists of
three main components: a sensor protein (receptor), an adapter protein and caspase-1 …
three main components: a sensor protein (receptor), an adapter protein and caspase-1 …
Targeting the inflammasome in cardiovascular disease
MB Olsen, I Gregersen, Ø Sandanger, K Yang… - Basic to Translational …, 2022 - jacc.org
The pathogenesis of cardiovascular disease (CVD) is complex and multifactorial, and
inflammation plays a central role. Inflammasomes are multimeric protein complexes that are …
inflammation plays a central role. Inflammasomes are multimeric protein complexes that are …
[HTML][HTML] Inflammasome, T lymphocytes and innate-adaptive immunity crosstalk: role in cardiovascular disease and therapeutic perspectives
D Pedicino, AF Giglio, A Ruggio… - Thrombosis and …, 2018 - thieme-connect.com
Over the past few decades, lot of evidences have shown atherosclerosis as a chronic
progressive disease with an exquisite inflammatory feature. More recently, the role of innate …
progressive disease with an exquisite inflammatory feature. More recently, the role of innate …