Hemodynamic effects of the angiotensin-converting enzyme inhibitor, ramipril, in patients with mild to moderate aortic stenosis and preserved left ventricular function

KD O'Brien, XQ Zhao, DM Shavelle… - Journal of …, 2004 - journals.sagepub.com
Background Angiotensin-converting enzyme (ACE) inhibitor use is presumed to be
contraindicated in patients with aortic stenosis (AS). We determined the hemodynamic …

A prospective, double-blind, randomized controlled trial of the angiotensin-converting enzyme inhibitor Ramipril In Aortic Stenosis (RIAS trial)

S Bull, M Loudon, JM Francis, J Joseph… - European Heart …, 2015 - academic.oup.com
Aims Angiotensin-converting enzyme (ACE) inhibitors improve left ventricular (LV)
remodelling and outcome in heart failure and hypertensive heart disease. They may be …

Short-term hemodynamic effect of angiotensin-converting enzyme inhibition in patients with severe aortic stenosis: a placebo-controlled, randomized study

M Dalsgaard, K Iversen, J Kjaergaard, P Grande… - American Heart …, 2014 - Elsevier
Background In patients with severe aortic stenosis (AS), treatment with angiotensin-
converting enzyme inhibitors has previously been considered contraindicated. However …

Safety and efficacy of angiotensin-converting enzyme inhibitors in symptomatic severe aortic stenosis: symptomatic cardiac obstruction–pilot study of enalapril in aortic …

A Chockalingam, S Venkatesan, T Subramaniam… - American heart …, 2004 - Elsevier
BACKGROUND: Animal models have demonstrated a benefit of angiotensin-converting
enzyme inhibitors (ACEI) in experimental aortic stenosis (AS), and intravenous nitroprusside …

Administration of angiotensin-converting enzyme inhibitors is associated with slow progression of mild aortic stenosis in Japanese patients

K Wakabayashi, T Tsujino, Y Naito, A Ezumi… - Heart and vessels, 2011 - Springer
It is almost unknown which demographic factors or medications affect the progression of
aortic stenosis (AS) in Japanese patients with mild AS. We identified a total of 194 patients …

ACE inhibition in aortic stenosis: dangerous medicine or golden opportunity?

HC Routledge, JN Townend - Journal of human hypertension, 2001 - nature.com
Conventionally angiotensin-converting enzyme (ACE) inhibitors are contraindicated in
patients with aortic stenosis. Abundant evidence is now available showing that angiotensin II …

Effects of angiotensin converting enzyme inhibitors in hypertensive patients with aortic valve stenosis: a drug withdrawal study

J Jimenez-Candil, J Bermejo, R Yotti, C Cortina… - Heart, 2005 - heart.bmj.com
Objective: To determine the effects of angiotensin converting enzyme (ACE) inhibitors in
hypertensive patients with aortic valve stenosis (AS). Design: Observational, drug …

Randomized, placebo-controlled trial of the angiotensin-converting enzyme inhibitor, ramipril, in patients with coronary or other occlusive arterial disease

S MacMahon, N Sharpe, G Gamble, A Clague… - Journal of the American …, 2000 - jacc.org
OBJECTIVES The primary objective of this study was to investigate the effects of the
angiotensin-converting enzyme (ACE) inhibitor, ramipril, on carotid atherosclerosis in …

Maximally recommended doses of angiotensin-converting enzyme (ACE) inhibitors do not completely prevent ACE-mediated formation of angiotensin II in chronic …

UP Jorde, PV Ennezat, J Lisker, V Suryadevara… - Circulation, 2000 - Am Heart Assoc
Background—The added benefits of angiotensin II type I receptor (AT1) blockers (ARBs) to
ACE inhibition suggests that recommended doses of ACE inhibitors provide only partial …

Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis

MA Nadir, L Wei, DHJ Elder, R Libianto, TK Lim… - Journal of the American …, 2011 - jacc.org
Objectives: The purpose of this study was to investigate the impact of renin-angiotensin
system blockade therapy on outcomes in aortic stenosis (AS). Background: Angiotensin …