The mammalian genome is depleted in CG dinucleotides, except at protected regions where
they cluster as CpG islands (CGIs). CGIs are gene regulatory hubs and serve as …

Vertebrate CpG islands (CGIs) are short interspersed DNA sequences that deviate
significantly from the average genomic pattern by being GC-rich, CpG-rich, and …

One clear hallmark of mammalian promoters is the presence of CpG islands (CGIs) at more
than two-thirds of genes, whereas TATA boxes are only present at a minority of promoters …

CpG islands (CGIs) are often considered as gene markers, but the number of CGIs varies
among mammalian genomes that have similar numbers of genes. In this study, we …

In vertebrates, cytosine-guanine (CpG) dinucleotides are predominantly methylated, with∼
80% of all CpG sites containing 5-methylcytosine (5mC), a repressive mark associated with …

CpG islands (CGIs) are CG‐rich stretches in the genome that are concentrated near the
transcription start sites (TSS) of genes. Genes that possess CGIs, such as the housekeeping …

CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of
most genes and often lack DNA methylation. Querying their apparent importance, the …

CpG islands (CGIs) represent a widespread feature of vertebrate genomes, being
associated with~ 70% of all gene promoters. CGIs control transcription initiation by …

CpG, 5′-C-phosphate-G-3′, islands (CGIs) have long been known for their association
with enhancers, silencers, and promoters, and for their epigenetic signatures. They are …

CpG islands (CGI) are critical genomic regulatory elements that support transcriptional
initiation and are associated with the promoters of most human genes. CGI are distinguished …