Virtually all normal cells can reproduce themselves. The germ cells, however, can initiate
reproduction of the entire organism. A special sequence of events, meiosis, is responsible …

The generation of artificial gametes is a real challenge for the scientific community today. In
vitro development of human eggs and sperm will pave the way for the understanding of the …

In addition to the great growing need for assisted reproduction technologies (ART),
additional solutions for patients without functional gametes are strongly needed. Due to …

BACKGROUND Recent progress in the formation of artificial gametes, ie gametes generated
by manipulation of their progenitors or of somatic cells, has led to scientific and societal …

BACKGROUND Recent progress in the formation of artificial gametes, ie gametes generated
from progenitors or somatic cells, has led to scientific and societal discussion about their use …

Sperm and eggs are essential cells for reproduction and fertility in mammals. Lack of sperm
production is one of the leading causes of infertility, a major and growing problem in the …

Germ cell development is a series of highly specialized processes through which diploid
pluripotent cells differentiate into haploid gametes. The processes include biologically …

Reconstitution in culture of biological processes, such as differentiation and organization, is
a key challenge in regenerative medicine, and one in which stem cell technology plays a …

Germ-line cells are responsible for transmitting genetic and epigenetic information across
generations, and ensuring the creation of new individuals from one generation to the next …

The birth of Louise Brown, the first IVF baby, in 1978 marked a breakthrough in infertility
treatment. In recent decades, several important new techniques have been introduced. One …