Development of a decellularized hypopharynx with vascular pedicle scaffold for use in reconstructing hypopharynx

N Hou, D Lv, X Xu, Y Lu, J Li, R Ma, Y Tang… - Artificial …, 2022 - Wiley Online Library
Background Hypopharynx reconstruction after hypopharyngectomy is still a great challenge.
Perfusion decellularization is for extracellular matrix (ECM) scaffolding and had been used …

[HTML][HTML] Engineered hypopharynx from coculture of epithelial cells and fibroblasts using poly (ester urethane) as substratum

Z Shen, J Chen, C Kang, C Gong, Y Zhu - BioMed Research …, 2013 - hindawi.com
Porous polymeric scaffolds have been much investigated and applied in the field of tissue
engineering research. Poly (ester urethane)(PEU) scaffolds, comprising pores of 1–20 μm in …

Tissue-engineered larynx using perfusion-decellularized technique and mesenchymal stem cells in a rabbit model

N Hou, P Cui, J Luo, R Ma, L Zhu - Acta oto-laryngologica, 2011 - Taylor & Francis
Conclusion: Reseeding mesenchymal stem cells (MSCs) into the decellularized laryngeal
muscle matrix for construction of a tissue-engineered larynx is feasible. This in vivo …

A preliminary study on the preparation of perfusion-decellularized laryngeal scaffold and the feasibility of laryngeal muscle reconstruction

N Hou, PC Cui, WX Chen, JS Luo… - … er bi yan hou tou Jing wai …, 2009 - europepmc.org
Objective To prepare a decellularized whole laryngeal scaffold by utilizing a perfusion-
decellularized technique, reseed cells on it, and construct decellularized laryngeal muscles …

Perfusion-Decellularized Larynx as a Natural 3D Scaffold in a Rabbit Model

JO Park, HY Park, SC Shin, DH Lee, BJ Lee - ORL, 2022 - karger.com
Introduction: Decellularized larynges could be used as scaffolds to regenerate the larynx.
The purpose of this study was to establish a perfusion decellularization protocol to produce …

[HTML][HTML] Skeletal muscle regeneration on protein-grafted and microchannel-patterned scaffold for hypopharyngeal tissue engineering

Z Shen, S Guo, D Ye, J Chen, C Kang, S Qiu… - BioMed research …, 2013 - hindawi.com
In the field of tissue engineering, polymeric materials with high biocompatibility like
polylactic acid and polyglycolic acid have been widely used for fabricating living constructs …

Tissue-engineered trachea using perfusion-decellularized technique and mesenchymal stem cells in a rabbit model

N Hou - Journal of Neurological Surgery Part B: Skull Base, 2012 - thieme-connect.com
Objectives: The extracellular matrix (ECM) and MSCs have been widely used for organ
reconstruction. Our study aimed to prepare a decellularized tracheal scaffold with a …

Application of xenogenic acellular dermal matrix in reconstruction of oncological hypopharyngeal defects

P Li, S Li, X Yang, Q Tang, X He, S Wang - European Archives of Oto …, 2016 - Springer
Acellular dermal matrix (ADM) can be used as a new membrane substitute for repairing
mucosal defects. The objective of this study is to explore the effectiveness of xenogenic …

Glottic regeneration with a tissue‐engineering technique, using acellular extracellular matrix scaffold in a canine model

M Kitamura, S Hirano, S Kanemaru… - Journal of tissue …, 2016 - Wiley Online Library
Acellular extracellular matrix scaffold derived from porcine urinary bladder (UBM) is
decellularized material that has shown success for constructive remodelling of various …

Clinical application of in situ tissue engineering using a scaffolding technique for reconstruction of the larynx and trachea

K Omori, Y Tada, T Suzuki, Y Nomoto… - Annals of Otology …, 2008 - journals.sagepub.com
Objectives: The objective of the present study was to demonstrate the efficacy of the clinical
application of in situ tissue engineering using a scaffolding technique for laryngeal and …