DNA methylation plays a key role in regulating eukaryotic gene expression. Although
mitotically heritable and stable over time, patterns of DNA methylation frequently change in …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …

DNA methylation is an epigenetic mark that has suspected regulatory roles in a broad range
of biological processes and diseases. The technology is now available for studying DNA …

DNA cytosine methylation is a central epigenetic modification which plays critical roles in
cellular processes including genome regulation, development and disease. Here, we review …

Cytosine methylation is the most common covalent modification of DNA in eukaryotes. DNA
methylation has an important role in many aspects of biology, including development and …

MethylCap-seq is a robust procedure for genome-wide profiling of DNA methylation. The
approach consists of the capture of methylated DNA using the MBD domain of MeCP2, and …

Genomic DNA methylation profiles exhibit substantial variation within the human population,
with important functional implications for gene regulation. So far little is known about the …

One of the most challenging projects in the field of epigenetics is the generation of detailed
functional maps of DNA methylation in different cell and tissue types in normal and disease …

DNA methylation stabilizes developmentally programmed gene expression states. Aberrant
methylation is associated with disease progression and is a common feature of cancer …