Bio-On-Magnetic-Beads (BOMB): Open platform for high-throughput nucleic acid extraction and manipulation

P Oberacker, P Stepper, DM Bond, S Höhn… - PLoS …, 2019 - journals.plos.org
Current molecular biology laboratories rely heavily on the purification and manipulation of
nucleic acids. Yet, commonly used centrifuge-and column-based protocols require …

Magnetic particles for the separation and purification of nucleic acids

S Berensmeier - Applied microbiology and biotechnology, 2006 - Springer
Nucleic acid separation is an increasingly important tool for molecular biology. Before
modern technologies could be used, nucleic acid separation had been a time-and work …

Manipulation and extraction of genomic DNA from cell lysate by functionalized magnetic particles for lab on a chip applications

SW Yeung, IM Hsing - Biosensors and Bioelectronics, 2006 - Elsevier
A novel approach for extracting living cells' genomic DNA materials utilizing functionalized
magnetic particles (MPs) is reported in this investigation. This strategy is amenable to …

On-chip bioanalysis with magnetic particles

N Pamme - Current opinion in chemical biology, 2012 - Elsevier
Magnetic particles can combine two very selective processes in bioanalysis: the specific
binding of analytes to the particle surface based on molecular recognition and the specific …

Continuous microfluidic DNA extraction using phase-transfer magnetophoresis

M Karle, J Miwa, G Czilwik, V Auwärter, G Roth… - Lab on a Chip, 2010 - pubs.rsc.org
This paper reports a novel microfluidic-chip based platform using “phase-transfer
magnetophoresis” enabling continuous biomolecule processing. As an example we …

Low-resource nucleic acid extraction method enabled by high-gradient magnetic separation

SI Pearlman, M Leelawong… - … applied materials & …, 2020 - ACS Publications
Nucleic acid-based diagnostic tests often require isolation and concentration of nucleic
acids from biological samples. Commercial purification kits are difficult to use in low …

Rapid and continuous magnetic separation in droplet microfluidic devices

E Brouzes, T Kruse, R Kimmerling, HH Strey - Lab on a Chip, 2015 - pubs.rsc.org
We present a droplet microfluidic method to extract molecules of interest from a droplet in a
rapid and continuous fashion. We accomplish this by first marginalizing functionalized super …

Mobile magnetic particles as solid-supports for rapid surface-based bioanalysis in continuous flow

SA Peyman, A Iles, N Pamme - Lab on a Chip, 2009 - pubs.rsc.org
An extremely versatile microfluidic device is demonstrated in which multi-step (bio) chemical
procedures can be performed in continuous flow. The system operates by generating …

Magnetic particles for integrated nucleic acid purification, amplification and detection without pipetting

Y Chen, Y Liu, Y Shi, J Ping, J Wu, H Chen - TrAC Trends in Analytical …, 2020 - Elsevier
Nucleic acid amplification based detection plays an important role in food safety,
environmental monitoring and clinical diagnosis. However, traditional nucleic acid detection …

Isolation of genomic DNA using magnetic nanoparticles as a solid-phase support

ZM Saiyed, CN Ramchand… - Journal of Physics …, 2008 - iopscience.iop.org
In recent years, techniques employing magnetizable solid-phase supports (MSPS) have
found application in numerous biological fields. This magnetic separation procedure offers …