An overview of ethologicall-based animal models suitable for investigating the
pharmacological treatment of anxiety disorders is presented. The DSM-IIIR classification …

Animal models for anxiety-related behavior are based on the assumption that anxiety in
animals is comparable to anxiety in humans. Being anxious is an adaptive response to an …

Animal models can certainly be useful to find out more about the biological bases of anxiety
disorders and develop new, more efficient pharmacological and/or behavioral treatments …

Rationale: There exists a wide range of animal models and measures designed to assess
anxiety or fearfulness. However, the relationship between these models and clinical anxiety …

This chapter critically discusses the process of developing, validating, and working with
animal models relevant to psychiatric disorders. A model is defined as any experimental …

An impressive number of animal models to assess depression and anxiety are available
today. However, the relationship between these models and the clinical syndromes of …

In the absence of fully characterized biological indexes, anxiety is at present measured as
unpleasant effects reported verbally by patients. Because of the subjective nature of the …

Among the multiple possibilities to study human pathologies, animal models remain one of
the most used pathways. They allow to access to unavailable answers in human patients …

Our analysis shows that there is a large interest in performing anxiety research innovatively.
However, efforts are highly divergent and result in large numbers of poorly validated and …

In the field of anxiety research, animal models are used as screening tools in the search for
compounds with therapeutic potential and as simulations for research on mechanisms …